Nonvariceal acute upper gastrointestinal bleeding is often associated with significant blood loss and anemia.
Both the bleeding episode itself and the subsequent anemia are likely to significantly impact a patientís health-related quality of life (HRQoL).
Treating the anemia is essential to increase the hemoglobin levels.
The HRQoL impact has not been investigated.
Drs Palle Bager and Jens Dahlerup performed a longitudinal study to determine the relationship between anemia, HRQoL, and fatigue in patients after nonvariceal acute upper gastrointestinal bleeding.
|Fatigue levels decreased from baseline to month 3 and month 6|
|Scandanavian Journal of Gastroenterology|
A total of 97 patients were followed in this longitudinal study with a 6-month follow-up.
The team reported that all patients had acute upper gastrointestinal bleeding and were anemic at inclusion.
Anemia, HRQoL, and fatigue were assessed at baseline, and at 1, 3, and 6 months.
The research team included the patients were initially in an iron supplementation study.
The team observed that patientsí HRQoL increased, and their fatigue levels decreased from baseline to month 3 and month 6.
The research team noted that approximately half of the patients had full health at month 3.
The team observed similar results in the general population.
At 3 and 6 months after the bleeding episodes, neither the HRQoL nor fatigue was affected by the anemia.
Dr Bager and colleagues comment, "This study did not uncover relationships between anemia and HRQoL or anemia and fatigue after nonvariceal acute upper gastrointestinal bleeding."