Capsule endoscopy is most commonly performed to evaluate obscure gastrointestinal bleeding.
However, at present the role of capsule endoscopy in patients with obscure-overt gastrointestinal bleeding especially during daily clinical practice is unknown.
Professor Panagiotis Katsinelos and colleagues from Greece investigated the diagnostic yield and the impact of capsule endoscopy on the management of patients with obscure-overt gastrointestinal bleeding.
Between 2007 and 2011, the team prospectively included all patients with obscure-overt gastrointestinal bleeding who underwent capsule endoscopy after negative bidirectional endoscopy.
Capsule endoscopy findings revealing the cause of bleeding, type of therapeutic intervention and clinical variables associated with positive capsule endoscopy and recurrence of gastrointestinal bleeding were evaluated.
The researchers enrolled 118 patients with a median age of 66 years.
|Overall diagnostic yield of the capsule endoscopy was 67%|
|Scandanavian Journal of Gastroenterology|
The team found that the overall diagnostic yield of the capsule endoscopy was 67%.
The most common findings were angiodysplasias, followed by ulcer, and tumors.
The research team noted that age and cardiovascular disease were significant clinical variables predicting the higher incidence of angiodysplasias.
Specific therapeutic interventions were undertaken in 68% of patients with positive capsule endoscopy.
Recurrence of gastrointestinal bleeding was observed in 1 patient with negative capsule endoscopy, and 20% of patients with positive capsule endoscopy.
The research team showed high age and no therapeutic intervention as significant factors associated with recurrent bleeding.
Dr Katsinelos' team comments, "Capsule endoscopy represents a promising diagnostic method in the investigation of obscure-overt gastrointestinal bleeding, with significant impact on its clinical management in daily clinical practice."