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 07 February 2016

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News

Rapid measure of IBD disease control from the patient's perspective

A team of doctors developed and validated a rapid, generic measure of disease control from the patient's perspective, using the IBD-Control questionnaire, reports July's issue of Gut.

News image

Introduction The use of patient reported outcome measures to support routine inflammatory bowel disease (IBD) care is not widespread, and suggests that existing questionnaires lack relevance to day-to-day decisions or are too cumbersome to administer.

Dr Keith Bodger and colleagues from the United Kingdom developed a simple, generic tool for capturing disease control from the patient's perspective to address these barriers.

Development based on literature review, patient focus groups/interviews and a steering group, defining a limited set of generic questions.

The ‘IBD-Control’ questionnaire comprises 13 items plus a visual analogue scale (VAS).

Completion time was 1 min 15 seconds
Gut

Prospective validation involved baseline completion of IBD-Control, quality of life (QoL) questionnaire (UK-IBD-Q), EuroQol (EQ-5D), Hospital Anxiety and Depression Score, and clinician assessment.

The team reported that 299 patients returned baseline surveys, and 138 attended for repeat visits.

The researchers observed that completion time was 1 min 15 seconds.

The team found a strong correlation between IBD-Control-8 and IBD-Control-VAS.

For test-retest reliability, the intra-class correlation was 0.97 for IBD-Control-8, and 0.96 for IBD-Control-VAS.

Construct validity showed moderate-to-strong correlations between IBD-Control-8 and IBD-Control-VAS versus activity indices, UK-IBD-Q and EQ-5D (utility) with r values 0.52–0.86.

Sensitivity to change demonstrated effect sizes of 0.76–1.44.

Dr Bodger and team conclude, "The IBD-Control is a rapid, reliable, valid and sensitive instrument for measuring overall disease control from the patient's perspective."

"Unlike existing patient reported outcome measures, its simplicity, ease-of-use and generic applicability make it a candidate for supporting routine care."

Gut 2014;63:1092-1102
10 June 2014

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