Help
Subscribe


All of GastroHep is now free access! - Click here to register Read For FREE - Our full range of review articles
GastroHep.com - the global online resource for all aspects of gastroenterology, hepatology and endoscopy
GastroHep.com - the global online resource for all aspects of gastroenterology, hepatology and endoscopy Profile of Guido Tytgat Profile of Pete Peterson Profile of Peter Cotton Profile of Roy Pounder

Home

News  
Journals
Review Articles
Slide Atlas
Video Clips
Online Books
Advanced Digestive Endoscopy
Classical Cases
Conference Diary
PubMed
International GH Links
USA GH Links
National GH Links
National GI Societies
Other Useful Links




Emails on Gastroenterology and Hepatology
the National AIDS Treatment Advocacy Project
Visit the gastroenterology section of the EUMS

News

A single histoacryl injection may be sufficient for bleeding gastric varices

A study published in the latest European Journal of Gastroenterology & Hepatology evaluates the efficacy and long-term outcomes of patients treated with a single session of histoacryl sclerotherapy for active gastric variceal bleeding.

News image

Gastric variceal bleeding is one of the most feared complications of portal hypertension and hence merits investigation for its optimal therapy.

Dr Ali Khawaja and colleagues evaluated the efficacy and long-term outcomes of patients treated with a single session of histoacryl sclerotherapy for active gastric variceal bleeding.

The medical records of patients who presented with active gastric variceal bleeding between 1998 and 2011 in a tertiary care setting were evaluated retrospectively and the eventual outcomes were assessed at least 1 year after the index bleed.

The research team evluated 97 patients.

The mean age of the patients was 51 years, of which 62% were men.

Hepatitis C was the most common etiology, found in 65% of patients.

Re-bleeding was seen in 27% of patients during the 1-year follow-up
European Journal Gastroenterology & Hepatology

The research team noted that the majority of the patients were classified as Child–Pugh grade B and C.

The team observed that a total of 41% of patients were IGV1, 36% of patients were GOV 2, 21% of patients were GOV 1, and 2% of patients were IGV2.

A single session of histoacryl was successful in controlling bleeding in 86% of patients.

The team reported that 7% patients died during the hospital stay.

The researchers observed rebleeding in 27% of patients during the 1-year follow-up, of whom 50% were managed successfully with repeated histoacryl injection.

The overall mortality rate at 6 weeks, 6 months, and 1 year was 14%, 20%, and 27% patients, respectively.

The team noted that Child–Pugh classification was a significant prognostic factor of survival.

Dr Khawaja's team concludes, "A single session of histoacryl sclerotherapy is effective in the majority of patients with active gastric variceal bleeding."

"Rebleeding was observed in one-fourth of patients, half of whom were controlled successfully by repeated histoacryl sclerotherapy."

Eur J Gastroenterol Hepatol 2014: 26(6): 661-667
23 May 2014

Go to top of page Email this page Email this page to a colleague

 30 June 2015

Advanced search
 30 June 2015 
NSAIDs and hearburn symptoms
 30 June 2015 
Glucocorticoids and peptic ulcer bleeding
 30 June 2015 
Split-dose preparations vs day-before bowel cleansing regimens
 29 June 2015 
Rescue therapy in ulcerative colitis
 29 June 2015 
Prevention of pancreatitis after ERCP
 29 June 2015 
Advances in autoimmune pancreatitis
 26 June 2015 

Gene polymorphism in alcoholic liver disease

 26 June 2015 
Dietary fibre–microbiota interactions
 26 June 2015 
Gastritis in celiac disease
 25 June 2015 
Persistent organ failure in acute cholangitis patients
 25 June 2015 
Vitamin D level and primary biliary cirrhosis
 25 June 2015 
Fecal microbiota in pediatric IBD
 24 June 2015 
Environmental risk in IBD
 24 June 2015 
Fatigue scales for IBD
 24 June 2015 
Mucosal healing tests in ulcerative colitis
 23 June 2015 
Marker associated with endoscopic lesion in Crohn's
 23 June 2015 
Body composition in children with IBD
 23 June 2015 
Medical vs nurse endoscopists
 22 June 2015 
Gene polymorphism associated with increased liver enzymes
 22 June 2015 
Treatment of uncomplicated acute appendicitis
 22 June 2015 
Solid organ cancers after liver transplant
 19 June 2015 
Causes of death in HBV
 19 June 2015 
Lifetime benefits of increased adenoma detection rates
 19 June 2015 
Acid-suppressive therapy before anti-reflux surgery
 18 June 2015 
Endoscopic activity in symptomatic IBD patients
 18 June 2015 
Regimens for H. pylori eradication
 18 June 2015 
Risk for dyspepsia
 17 June 2015 
Non-invasive markers of advanced liver fibrosis
 17 June 2015 
Patients’ and clinicians’ perception of pouch dysfunction
 17 June 2015 
NAFLD risk in celiac disease
 16 June 2015 
Esophageal food bolus impaction
 16 June 2015 
Evaluating lymph node metastasis for rectal cancer
 16 June 2015 
Risk score for hepatocellular carcinoma screening
 15 June 2015 
Low-cost colonoscopy training
 15 June 2015 
Determining dysbiosis in IBS or IBD
 15 June 2015 
Light alcohol consumption and NAFLD
 12 June 2015 
Smoking and disease course in IBD
 12 June 2015 
Hep D in a Hep B endemic area
 12 June 2015 
Patient-orientated internet information in ulcerative colitis
 11 June 2015 
Physical inactivity and NAFLD
 11 June 2015 
Esophageal stricture after endoscopic resection
 11 June 2015 
Guideline based screening strategies for hepatitis
 10 June 2015 
Cost-effectiveness of HCV treatment in liver disease
 10 June 2015 
Abdominoperineal excision for low rectal cancer
 10 June 2015 
Pediatric chronic Hep C
 09 June 2015 
Bile acid malabsorption in IBS
 09 June 2015 
Racial differences in celiac disease
 09 June 2015 
Conversion from laparoscopic to open colorectal cancer resection
 08 June 2015 
Short sleep duration and NAFLD
 08 June 2015 
Heritability in inflammatory bowel disease
 08 June 2015 
Eosinophilic esophagitis
 05 June 2015 
In-hospital mortality in patients with lower GI bleeding
 05 June 2015 
Scoring system for microscopic colitis
 05 June 2015 
H. pylori and myocardial infarction
 04 June 2015 
Mucosal healing in celiac disease and pregnancy
 04 June 2015 
Gastrointestinal microbiomes in Crohn's
 04 June 2015 
Dyspepsia in the community:
 03 June 2015 
Predicting disease activity in IBD
 03 June 2015 
Outcomes with discontinuation of therapy in Crohn's
 03 June 2015 
Biopsies in eosinophilic esophagitis

Blackwell Publishing


GastroHep.com is a Blackwell Publishing registered trademark
© 2015 Wiley-Blackwell and GastroHep.com and contributors
Privacy Statement
Disclaimer
About Us