Help
Subscribe


All of GastroHep is now free access! - Click here to register Read For FREE - Our full range of review articles
GastroHep.com - the global online resource for all aspects of gastroenterology, hepatology and endoscopy
GastroHep.com - the global online resource for all aspects of gastroenterology, hepatology and endoscopy Profile of Guido Tytgat Profile of Pete Peterson Profile of Peter Cotton Profile of Roy Pounder

Home

News  
Journals
Review Articles
Slide Atlas
Video Clips
Online Books
Advanced Digestive Endoscopy
Classical Cases
Conference Diary
PubMed
International GH Links
USA GH Links
National GH Links
National GI Societies
Other Useful Links




Emails on Gastroenterology and Hepatology
the National AIDS Treatment Advocacy Project
Visit the gastroenterology section of the EUMS

News

Barrett's esophagus and esophageal cancer is levelling off in Europe

Barrett's esophagus and esophageal adenocarcinoma in the United Kingdom and the Netherlands is levelling off, reports the latest issue of the Alimentary Pharmacology & Therapeutics.

News image

Barrett's esophagus is a risk factor for esophageal adenocarcinoma.

Several studies report increasing incidences of Barrett's esophagus with substantial variation.

Dr Masclee and colleagues from the Netherlands determined age- and sex-stratified incidence rates of Barrett's esophagus and esophageal adenocarcinoma.

The team performed a cohort study using 2 primary care databases in the United Kingdom and the Netherlands.

Barrett's esophagus and esophageal adenocarcinoma cases were identified using disease-specific READ codes, and free-text search with manual validation.

Age- and sex-specific incidence rates were calculated for both Barrett's esophagus and esophageal adenocarcinoma.
Incident rates of Barrett's was 24 times higher in males across all age groups
Alimentary Pharmacology & Therapeutics

From the study population of 6,885,420 subjects in the UK, the team identified 12,312 incident Barrett's esophagus, and 40 subsequent incident esophageal adenocarcinoma cases.

There were 1383 incident Barrett's esophagus, and subsequent 5 incident esophageal adenocarcinoma cases among the 1,487,191 subjects in the Netherlands.

The team found that the incident rate of Barrett's esophagus increased linearly with age, and was 16 per 100,000 PYs in the United Kingdom, and 24 per 100,000 PYs in the Netherlands for patients aged 4044 years, increasing to 86 per 100,000 PYs in the United Kingdom, and 87 per 100,000 PYs in the Netherlands for 7074 years.

In both the United Kingdom and the Netherlands, incident rates of Barrett's esophagus was 24 times higher in males than females across all age groups.

The team observed that with respect to calendar time, the incident rate of Barrett's esophagus increased by 35% in the United Kingdom, and 41% in the Netherlands from 2000 to 2003, after which incident rates remained stable until 2012.

Dr Masclee's team concludes, "The incidence rates of Barrett's esophagus in the United Kingdom and the Netherlands increased until 2003, but levelled off thereafter."

"Around 0.3% of patients with Barrett's esophagus developed esophageal adenocarcinoma at least 1 year after Barrett's esophagus diagnosis. "

"These findings may help tailor endoscopic surveillance strategies among patients with Barrett's esophagus."

Aliment Pharmacol Ther 2014: 39(11): 13211330
22 May 2014

Go to top of page Email this page Email this page to a colleague

 23 May 2015

Advanced search
 22 May 2015 
Treatment with anti-integrin antibodies in IBD
 22 May 2015 
Care of patients with GERD
 22 May 2015 
Colonoscopy screening for colorectal cancer
 21 May 2015 
Imaging for hepatocellular carcinoma
 21 May 2015 
Lymphoma in IBD
 21 May 2015 
Serrated polyps and colorectal cancer
 20 May 2015 
Refractory metastatic colorectal cancer
 20 May 2015 
Pancreatic neuroendocrine tumors
 20 May 2015 
Surveillance in long-segment Barrett's
 19 May 2015 
PPIs and cryptogenic liver abscess
 19 May 2015 
Anti-integrin antibodies in IBD
 19 May 2015 
Metabolic syndrome and Barrett's
 18 May 2015 
HLA haplotypes and primary sclerosing cholangitis
 18 May 2015 
Safety of PPI
 18 May 2015 
ESPGHAN celiac guidelines
 15 May 2015 
Management of nonhospitalized ulcerative colitis
 15 May 2015 
Diabetes and infections in IBD with immunomodulation
 15 May 2015 
Microscopic colitis risk with PPIs/NSAIDs
 14 May 2015 
Diagnosis of spontaneous bacterial peritonitis
 14 May 2015 
Mortality in US patients with cirrhosis
 14 May 2015 
Radiation exposure during ERCP
 13 May 2015 
Predictors of IBD
 13 May 2015 
Psychological distress and liver disease mortality
 13 May 2015 
Hypnotherapy in IBS/IBD
 12 May 2015 
Bleeding in NSAID users with H.pylori
 12 May 2015 
Capsule colonoscopy detects colorectal polyps
 12 May 2015 
Anti-TNF biologics in acute severe ulcerative colitis
 11 May 2015 
Management of Barrett's esophagus
 11 May 2015 
Marker to detect recurrence of Crohn's
 11 May 2015 
Thalidomide for IBD
 08 May 2015 
Surveillance colonoscopy in colorectal cancer
 08 May 2015 
HCV treatment with compensated cirrhosis
 08 May 2015 
Medical management of Crohn's
 07 May 2015 
Surgical complications in ulcerative colitis
 07 May 2015 
Combination therapy for noncirrhostic patients
 07 May 2015 
Anxiety and new-onset dyspepsia
 06 May 2015 
PPIs and spontaneous bacterial peritonitis
 06 May 2015 
Infant feeding and celiac disease
 06 May 2015 
Preventing recurrent C. diff infection
 05 May 2015 
Fatigue in primary sclerosing cholangitis
 05 May 2015 
Annual CT scans after esophagectomy for cancer
 05 May 2015 
Prevalence of eosinophilic esophagitis
 04 May 2015 
Stress resilience and peptic ulcer disease
 04 May 2015 
Endoscope storage and microbial colonization
 04 May 2015 
Menarche and NAFLD
 01 May 2015 
Sleep and physical activity measured in Crohn's
 01 May 2015 
NAFLD progression from steatosis to fibrosing-steatohepatitis
 01 May 2015 
Dietary supplement hepatotoxicity
 30 April 2015 
Botulinum toxin A for the treatment of obesity
 30 April 2015 
Risk factors for primary sclerosing cholangitis
 30 April 2015 
Neoadjuvant chemoradiotherapy for esophageal cancer
 29 April 2015 
Liver enzyme elevations after anti-TNF therapy in IBD

 29 April 2015 
Hepatocellular carcinoma surveillance in HBV
 29 April 2015 
Response to sorafenib in hepatocellular carcinoma
 28 April 2015 
Risk factors of hepatocellular carcinoma
 28 April 2015 
Clinical outcomes after esophagectomy
 28 April 2015 
Alcohol drinking and risk of liver cirrhosis
 23 April 2015 
Gut microbiota modulation for alcoholic liver disease
 23 April 2015 
Moderate sodium restriction diet in cirrhosis
 23 April 2015 
Gastroesophageal junction disruption and obesity

Blackwell Publishing


GastroHep.com is a Blackwell Publishing registered trademark
© 2015 Wiley-Blackwell and GastroHep.com and contributors
Privacy Statement
Disclaimer
About Us