Gastroenteritis with Campylobacter concisus is an emerging infection, but the risk of irritable bowel syndrome (IBS) following it is unknown.
Dr Hans Linde Nielsen and colleagues from Denmark performed a prospective, community-based study of gastroenteritis with C. concisus and C. jejuni/coli.
The team invited adult patients to participate in a questionnaire study, including IBS symptoms and psychometric scores, at baseline and at 6 months.
The researchers estimated adjusted relative risk for IBS as the primary outcome.
The development of IBS symptoms at 6 months was reported in 25% of patients with C. concisus infection, and in 19% of C. jejuni/coli patients.
|Gastroenteritis with C. concisus carries a 25% risk of IBS at 6-month follow-up|
|Scandanavian Journal of Gastroenterology|
The team noted that the baseline predictors for IBS in C. concisus infection were high anxiety scores, chills, headache, dizziness, and muscle ache.
For all Campylobacter patients, the team confirmed previous reports of anxiety, depression, and high somatization scores as predictors for post-infectious IBS.
Dr Nielsen and team conclude, "Gastroenteritis with C. concisus carries a 25% risk of IBS at 6-month follow-up."
"The risk factors for IBS are chills, headache, dizziness and muscle ache in the acute stage, as well as preexisting high psychometric scores for anxiety."
"Our findings suggest that psychological factors play a role in the development of post-infectious IBS."