The increasing incidence of microscopic colitis has been partly attributed to detection bias.
Dr Darrell Pardi and colleagues ascertained recent incidence trends, and the overall prevalence of microscopic colitis in a population-based study.
Using data from the Rochester Epidemiology Project, the researchers identified residents of Olmsted County, Minnesota, who were diagnosed with collagenous colitis or lymphocytic colitis from 2002 to 2010, based on biopsy results and the presence of diarrhea.
Poisson regression analyses were performed to evaluate associations between incidence and age, sex, and calendar period.
|Increasing age was associated with increasing incidence|
|Clinical Gastroenterology & Hepatology|
The team found that the age- and sex-adjusted incidence of microscopic colitis was 21 cases per 100,000 person-years.
The researchers noted that the incidence of lymphocytic colitis was 12 per 100,000 person-years, and collagenous colitis was 9 per 100,000 person-years.
The team noted that the incidence of microscopic colitis and its subtypes remained stable over the study period.
Increasing age and female sex were associated with increasing incidence.
In 2010, the prevalence of microscopic colitis was 219 cases per 100,000 persons.
Dr Pardi's team comments, "The incidence of microscopic colitis in Olmsted County residents has stabilized, and remains associated with female sex and increasing age."