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News

Small particle size diet reduces upper GI symptoms in diabetic gastroparesis

The most recent issue of the American Journal of Gastroenterology evaluated GI symptoms in insulin treated patients with diabetes and gastroparesis eating a diet with small particle size.

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Gastroparesis is a well-known complication to diabetes mellitus (DM). Dietary advice is considered to be of importance to reduce gastrointestinal (GI) symptoms in patients with diabetic gastroparesis, but no randomized controlled trials exist.

Dr Magnus Simrén and colleagues from Sweden compared GI symptoms in insulin treated DM subjects with gastroparesis eating a diet with small particle size (“intervention diet”) with the recommended diet for DM (“control diet”).

The team randomized 56 subjects with insulin treated DM and gastroparesis to the intervention diet or the control diet.

The patients received dietary advice by a dietitian at 7 occasions during 20 weeks.

Anxiety was reduced after the intervention diet
American Journal of Gastroenterology

GI symptom severity, nutrient intake and glycemic control were measured before and after the intervention.

A significantly greater reduction of the severity of the key gastroparetic symptoms—nausea/vomiting, postprandial fullness, and bloating—were seen in patients who received the intervention diet compared with the control diet, and this was also true for regurgitation/heartburn, but not for abdominal pain.

The team observed that anxiety was reduced after the intervention diet, but not after the control diet, whereas no effect on depression or quality of life was noted in any of the groups.

A higher fat intake in the intervention group was noted, but otherwise no differences in body weight, HbA1c or nutrient intake were seen.

Dr Simrén's team commented, "A small particle diet improves the key symptoms of gastroparesis in patients with diabetes mellitus."

Am J Gastroenterol 2014; 109: 375–385
14 March 2014

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