Help
Subscribe


GastroHep.com - the global online resource for all aspects of gastroenterology, hepatology and endoscopy

 30 June 2016

Advanced search
GastroHep.com - the global online resource for all aspects of gastroenterology, hepatology and endoscopy Profile of Roy Pounder

Home

News  
Journals
Review Articles
Slide Atlas
Video Clips
Online Books
Advanced Digestive Endoscopy
Classical Cases
Conference Diary
PubMed
International GH Links
USA GH Links
National GH Links
National GI Societies
Other Useful Links




Emails on Gastroenterology and Hepatology
the National AIDS Treatment Advocacy Project
Visit the gastroenterology section of the EUMS

News

East–West gradient in the incidence of IBD in Europe

The latest issue of Gut investigates the East–West gradient in the incidence of IBD in Europe.

News image

The incidence of inflammatory bowel disease (IBD) is increasing in Eastern Europe.

The reasons for these changes remain unknown.

Dr Burisch and colleagues from Denmark investigated whether an East–West gradient in the incidence of IBD in Europe exists.

A prospective, uniformly diagnosed, population based inception cohort of IBD patients in 31 centres from 14 Western, and 8 Eastern European countries covering a total background population of approximately 10.1 million people was created.

One-third of the centers had previous experience with inception cohorts.

35% were diagnosed with Crohn's disease
Gut

Patients were entered into a low cost, web based epidemiological database, making participation possible regardless of socioeconomic status and prior experience.

The research team evaluated 1515 patients aged 15 years or older, of whom 35% were diagnosed with Crohn's disease, 54% with ulcerative colitis, and 11% with IBD unclassified (IBDU).

The team observed that the overall incidence rate ratios in all Western European centres were 1.9 for Crohn's disease, and 2.1 for ulcerative colitis compared with Eastern European centers.

The median crude annual incidence rates per 100,000 in 2010 for Crohn's disease were 7 in Western European centers, and 3 in Eastern European centers, for ulcerative colitis 11 and 4, respectively, and for IBDU 2 and 0, respectively.

In Western Europe, 92% of Crohn's disease, 78% of ulcerative colitis, and 74% of IBDU patients had a colonoscopy performed as the diagnostic procedure compared with 90%, 100% and 96%, respectively, in Eastern Europe.

The researchers found that 8% of Crohn's disease, and 1% of ulcerative colitis patients in both regions underwent surgery within the first 3 months of the onset of disease.

The team noted that 7% of Crohn's disease patients, and 3% of ulcerative colitis patients from Western Europe received biological treatment as rescue therapy.

Of all European Crohn's disease patients, 20% received only 5-aminosalicylates as induction therapy.

Dr Burisch's team comments, "An East–West gradient in IBD incidence exists in Europe."

"Among this inception cohort—including indolent and aggressive cases—international guidelines for diagnosis and initial treatment are not being followed uniformly by physicians."

Gut 2014; 63: 588-597
10 March 2014

Go to top of page Email this page Email this page to a colleague

 30 June 2016 
IBS-type symptoms in pediatric IBD
 30 June 2016 
Antibiotics in children and obesity
 30 June 2016 
Staging system for familial adenomatous polyposis
 29 June 2016 
Anti-tumor necrosis factor in mothers and newborns
 29 June 2016 
Hep C eradication in people who inject drugs
 29 June 2016 
Progression to esophageal carcinoma in Barrett's
 28 June 2016 
Cancer recurrence after immune-suppressive therapies
 28 June 2016 
Gastric cancer screening in the USA
 28 June 2016 
Acute severe ulcerative colitis
 27 June 2016 
Epidemiology of NAFLD
 27 June 2016 
Tobacco smoking and ulcerative colitis
 27 June 2016 
The Toronto Consensus for H. pylori treatment
 24 June 2016 
Dietary trends in the USA
 24 June 2016 
Statins and colorectal cancer in IBD
 24 June 2016 
Fibre for chronic idiopathic constipation
 23 June 2016 
Biomarker for eosinophilic esophagitis diagnosis
 23 June 2016 
Touch screens in the IBD outpatient clinic
 23 June 2016 
Adverse events after colonoscopy bowel preparations
 22 June 2016 
Benefits and harms of colorectal cancer screening
 22 June 2016 
IBS symptoms in IBD
 22 June 2016 
Outcomes among US veterans with Hep B
 21 June 2016 
Screening for colorectal cancer
 21 June 2016 
Tenofovir and Hep B transmission in mothers
 21 June 2016 
Access to liver subspecialty care and survival
 20 June 2016 
Genes for colorectal cancer risk
 20 June 2016 
Patients and gastroenterologists’ perceptions on IBD
 20 June 2016 
Hep C treatment in people who inject drugs
 17 June 2016 
Noninvasive markers of liver fibrosis
 17 June 2016 
Predictors of starting with long-term PPIs
 17 June 2016 
Extrahepatic manifestations of Hep C
 16 June 2016 
Assessing progression of NAFLD
 16 June 2016 
Endotracheal intubation and endoscopy unit efficiency metrics
 16 June 2016 
Bile acid diarrhea
 15 June 2016 
Consensus for acute severe ulcerative colitis
 15 June 2016 
Dental erosions in GERD
 15 June 2016 
Pharmacological treatments for obesity with weight loss
 14 June 2016 
Antibiotics and gut inflammation
 14 June 2016 
Liver-related mortality in the developed world
 14 June 2016 
Hep C patient outcomes treated with different anti-viral regimens
 13 June 2016 
Obesity in the USA
 13 June 2016 
Celiac disease drug development
 13 June 2016 
Pneumonia risk in celiac disease
 10 June 2016 

Celiac disease drug development

 10 June 2016 
Rectal cancer surgery checklist
 10 June 2016 
Breath as a marker for IBS
 09 June 2016 
Psychological morbidity in young people with IBD
 09 June 2016 
Predicting hepatic encephalopathy in cirrhosis
 09 June 2016 
Evaluation of endoscopic findings from patients with Crohn's
 08 June 2016 
Adult obesity trends in the USA
 08 June 2016 
Pediatric IBD unclassified vs other IBD
 08 June 2016 
Dark chocolate and NASH oxidation
 07 June 2016 
Flexible endoscopy for Zenker's diverticulum
 07 June 2016 
Predicting risk of hepatic encephalopathy in cirrhosis
 07 June 2016 
Electronic learning system for colon capsule endoscopy
 06 June 2016 
Disturbed sleep and symptoms in IBS
 06 June 2016 
Oral contraceptives and Crohn’s complications
 06 June 2016 
Eosinophilic esophagitis
 03 June 2016 
Antibiotic prophylaxis in cirrhosis
 03 June 2016 
Mortality in hospitalized peptic ulcer patients
 03 June 2016 
Decision aid for surgical patients with ulcerative colitis

Blackwell Publishing


GastroHep.com is a Blackwell Publishing registered trademark
© 2016 Wiley-Blackwell and GastroHep.com and contributors
Privacy Statement
Disclaimer
About Us