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PillCam small bowel capsule endoscopy gastric passage interval association with pathological findings

A study in January's issue of the European Journal of Gastroenterology & Hepatology investigates the association of pillCam small bowel capsule endoscopy gastric passage interval with patient's complaints and pathological findings.

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Prolonged gastric transit interval of small bowel video capsule endoscopy (SBCE) can potentially indicate a motility disorder and disrupt whole small bowel visualization.

Dr Dan Carter and colleagues prospectively examined the association of prolonged gastric passage interval with symptoms, anthropometric and laboratory factors, and factors related to the SBCE examination, such as indications and pathological findings.

The team performed a prospective single-center study that included 100 patients who underwent SBCE for any indication.

Before the examination, clinical, demographic, and anthropometric data were recorded.

The patients filled the Gastroparesis Cardinal Symptoms Index (GCSI) questionnaire.

76 patients had normal gastric passage interval
European Journal of Gastroenterology & Hepatology

The researchers assessed the difference in the study parameters between the prolonged gastric transit (≥45 min) group and the group with a normal gastric transit.

The research team reported that 76 patients had normal gastric passage interval, and 24 patients had prolonged gastric passage interval.

No significant differences were found between the groups in age, sex, prevalence of diabetes mellitus, use of antimotility drugs, indications for the exam and levels of hemoglobin, C-reactive protein, and albumin.

Esophageal and small bowel transition intervals did not vary between both groups.

The researchers noted that the mean score for any GCSI item, and the mean total GCSI score did not differ significantly between the normal and the prolonged gastric passage interval groups.

There were no significant differences between the groups in pathological findings in the small bowel.

Dr Carter's team concludes, "In the study population, prolonged SBCE gastric transit interval had no clinical significance, and therefore, probably does not mandate any further gastrointestinal evaluation."

Eur J Gastroenterol Hepatol 2014: 26(1): 47-51
16 December 2013

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