Stress is believed to play a role in the pathogenesis of functional gastrointestinal disorders.
Dr Kwang Jae Lee and colleagues from Korea investigated the effect of acute auditory stress on gastric motor responses to a meal in healthy subjects.
A total of 8 healthy volunteers who had no recurrent gastrointestinal symptoms participated in the prospective, randomized, crossover study.
Gastric half-emptying time and meal-induced proximal gastric accommodation were measured using gastric scintigraphy under the auditory stress and control conditions in a randomized crossover design.
|Severity scores of postprandial epigastric discomfort were higher under the stress condition |
|Journal of Gastroenterology & Hepatology|
The researchers found that gastric half-emptying time under the stress condition was significantly longer than that under the control condition.
Under the stress and control conditions, the proximal gastric volume significantly increased after a meal.
The research team noted that the degree of the postprandial increase in proximal gastric volume did not significantly differ between both conditions.
The research team found that severity scores of postprandial epigastric discomfort and fullness were significantly higher under the stress condition than under the control condition.
Dr Lee's team concludes, "Acute auditory stress delays gastric emptying and increases the severity of postprandial symptoms in the healthy subjects, suggesting the relevance of psychological stress to the pathophysiological mechanism of functional dyspepsia."