Dr Brian Pike and colleagues from Maryland, USA performed a systematic review and meta-analysis was to estimate the risk of developing functional dyspepsia following acute infectious gastroenteritis.
Eligible studies were identified through PubMed and EMBASE searches.
Data and quality indicators were extracted by 2 authors from 9 studies examining the risk of functional dyspepsia following infectious gastroenteritis in 5,755 exposed individuals.
|Quality indicators were extracted by 2 authors from 9 studies|
|American Journal of Gastroenterology|
The research team noted that estimates of functional dyspepsia risk following infectious gastroenteritis based on a random effects model yielded a pooled odds ratio of 2.18.
Subanalyses revealed differences in the odds of funcitonal dyspepsia following self-reported acute infectious gastroenteritis compared with documented acute infectious gastroenteritis medical encounters, and a decreasing functional dyspepsia risk with time from infectious gastroenteritis.
Dr Pike's team concludes, "Taken together, these data suggest that the risk of developing functional dyspepsia is significantly increased following infectious gastroenteritis."