Few studies have analyzed the safety of endoscopy in patients with inflammatory bowel disease (IBD).
Dr Jason Ferreira and colleagues from Massachusetts, USA determined the prevalence of procedure-related complications among these patients, compared with the general population, and estimated the lifetime risk of colonoscopy-related complications.
The research team collected data on complications in 685 patients with IBD, and 17,000 patients without IBD (controls) using an automated system to track all emergency department visits to the Beth Israel Deaconess Medical Center within 14 days of an endoscopic procedure.
The team reviewed charts of all IBD patients to determine health care use or visits to a gastroenterologist or primary care physician and visits to other emergency departments or hospitals) after endoscopy.
The lifetime risk of procedure-related complications was estimated using a Markov Monte Carlo model.
|Risk of complications after surveillance colonoscopy was 13% in IBD|
|Clinical Gastroenterology & Hepatology|
The researchers found that rates of complications were 1.17% among patients with IBD, and 0.96% among controls.
The chart review showed that 4% of the IBD cohort received medical care within 14 days of the endoscopic procedure.
Based on a Markov Monte Carlo simulation model, the lifetime risk of complications after a surveillance colonoscopy protocol was 13% among patients with IBD, and 2% in the general population undergoing screening colonoscopy.
Dr Ferreira's team concludes, "Although the risk of adverse events after each endoscopic procedure was similar for patients with IBD and the general population, IBD patients have an increased lifetime risk of complications after colonoscopies."
"A higher percentage of patients with IBD also seek medical care after endoscopic procedures than controls."