Help
Subscribe


All of GastroHep is now free access! - Click here to register Read For FREE - Our full range of review articles
GastroHep.com - the global online resource for all aspects of gastroenterology, hepatology and endoscopy
GastroHep.com - the global online resource for all aspects of gastroenterology, hepatology and endoscopy Profile of Guido Tytgat Profile of Pete Peterson Profile of Peter Cotton Profile of Roy Pounder

Home

News  
Journals
Review Articles
Slide Atlas
Video Clips
Online Books
Advanced Digestive Endoscopy
Classical Cases
Conference Diary
PubMed
International GH Links
USA GH Links
National GH Links
National GI Societies
Other Useful Links




Emails on Gastroenterology and Hepatology
the National AIDS Treatment Advocacy Project
Visit the gastroenterology section of the EUMS

News

Factors that predict short-term intensive care unit mortality in cirrhosis

The most recent issue of Clinical Gastroenterology & Hepatology identifies factors that predict short-term intensive care unit mortality in patients with cirrhosis.

News image

Despite advances in critical care medicine, the mortality rate is high among critically ill patients with cirrhosis.

Dr Ranjeeta Bahirwani and colleagues from Pensylvania, USA identified factors that predict early mortality among patients with cirrhosis admitted to the intensive care unit, and developed a risk-stratification model.

The doctors collected data from patients with cirrhosis admitted to the intensive care unit at Indiana University intensive care unit from 2006, through 2009, or at the University of Pennsylvania intensive care unit from 2005, through 2010.

Factors associated with mortality within 7 days of admission were determined by logistic regression analyses.

A MELD score of 32 at ICU admission had a mortality of 54%
Clinical Gastroenterology and Hepatology

A model was constructed based on the predictive parameters available on the first day of intensive care unit admission in the Indiana University intensive care unit cohort, and then validated in the Penn-intensive care unit cohort.

The researchers found that Model for End-stage Liver Disease scores at intensive care unit admission were 25 in the Indiana University intensive care unit cohort, and 32 in the Penn-intensive care unit cohort.

The team found that corresponding 7-day mortalities were 28%, and 54%, respectively.

Model for End-stage Liver Disease score odds ratio of 1.13 and mechanical ventilation were associated independently with 7-day mortality in the Indiana University intensive care unit.

A model based on these 2 variables separated Indiana University intensive care unit patients into low-, medium-, and high-risk groups.

The team observed that these groups had 7-day mortalities of 9%, 27%, and 74%, respectively.

The team applied the model to the Penn–intensive care unit cohort, and found that the low-, medium-, and high-risk groups had 7-day mortalities of 33%, 56%, and 71%, respectively.

Dr Bahirwani's team concludes, "A model based on Model for End-stage Liver Disease score and mechanical ventilation on day 1 can stratify risk of early mortality in patients with cirrhosis admitted to the intensive care unit."

"More studies are needed to validate this model and to enhance its clinical utility."

Clin Gastroenterol and Hepatol 2013: 11(9): 1194-1200
18 September 2013

Go to top of page Email this page Email this page to a colleague

 01 July 2015

Advanced search
 01 July 2015 
Oral mechanical bowel preparation
 01 July 2015 
Missed gastric cancers
 01 July 2015 
Probiotics in IBD
 30 June 2015 
Split-dose preparations vs day-before bowel cleansing regimens
 30 June 2015 
Glucocorticoids and peptic ulcer bleeding
 30 June 2015 
NSAIDs and hearburn symptoms
 29 June 2015 
Prevention of pancreatitis after ERCP
 29 June 2015 
Advances in autoimmune pancreatitis
 29 June 2015 
Rescue therapy in ulcerative colitis
 26 June 2015 

Gene polymorphism in alcoholic liver disease

 26 June 2015 
Dietary fibre–microbiota interactions
 26 June 2015 
Gastritis in celiac disease
 25 June 2015 
Persistent organ failure in acute cholangitis patients
 25 June 2015 
Vitamin D level and primary biliary cirrhosis
 25 June 2015 
Fecal microbiota in pediatric IBD
 24 June 2015 
Fatigue scales for IBD
 24 June 2015 
Mucosal healing tests in ulcerative colitis
 24 June 2015 
Environmental risk in IBD
 23 June 2015 
Marker associated with endoscopic lesion in Crohn's
 23 June 2015 
Body composition in children with IBD
 23 June 2015 
Medical vs nurse endoscopists
 22 June 2015 
Gene polymorphism associated with increased liver enzymes
 22 June 2015 
Treatment of uncomplicated acute appendicitis
 22 June 2015 
Solid organ cancers after liver transplant
 19 June 2015 
Causes of death in HBV
 19 June 2015 
Lifetime benefits of increased adenoma detection rates
 19 June 2015 
Acid-suppressive therapy before anti-reflux surgery
 18 June 2015 
Endoscopic activity in symptomatic IBD patients
 18 June 2015 
Regimens for H. pylori eradication
 18 June 2015 
Risk for dyspepsia
 17 June 2015 
NAFLD risk in celiac disease
 17 June 2015 
Non-invasive markers of advanced liver fibrosis
 17 June 2015 
Patients’ and clinicians’ perception of pouch dysfunction
 16 June 2015 
Risk score for hepatocellular carcinoma screening
 16 June 2015 
Esophageal food bolus impaction
 16 June 2015 
Evaluating lymph node metastasis for rectal cancer
 15 June 2015 
Low-cost colonoscopy training
 15 June 2015 
Determining dysbiosis in IBS or IBD
 15 June 2015 
Light alcohol consumption and NAFLD
 12 June 2015 
Smoking and disease course in IBD
 12 June 2015 
Hep D in a Hep B endemic area
 12 June 2015 
Patient-orientated internet information in ulcerative colitis
 11 June 2015 
Physical inactivity and NAFLD
 11 June 2015 
Esophageal stricture after endoscopic resection
 11 June 2015 
Guideline based screening strategies for hepatitis
 10 June 2015 
Cost-effectiveness of HCV treatment in liver disease
 10 June 2015 
Abdominoperineal excision for low rectal cancer
 10 June 2015 
Pediatric chronic Hep C
 09 June 2015 
Bile acid malabsorption in IBS
 09 June 2015 
Racial differences in celiac disease
 09 June 2015 
Conversion from laparoscopic to open colorectal cancer resection
 08 June 2015 
Short sleep duration and NAFLD
 08 June 2015 
Heritability in inflammatory bowel disease
 08 June 2015 
Eosinophilic esophagitis
 05 June 2015 
In-hospital mortality in patients with lower GI bleeding
 05 June 2015 
Scoring system for microscopic colitis
 05 June 2015 
H. pylori and myocardial infarction
 04 June 2015 
Mucosal healing in celiac disease and pregnancy
 04 June 2015 
Gastrointestinal microbiomes in Crohn's
 04 June 2015 
Dyspepsia in the community:

Blackwell Publishing


GastroHep.com is a Blackwell Publishing registered trademark
© 2015 Wiley-Blackwell and GastroHep.com and contributors
Privacy Statement
Disclaimer
About Us