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Factors that influence the incidence of acute pancreatitis

A study published in the Alimentary Pharmacology & Therapeutics evaluates the impact of social deprivation, alcohol consumption, seasonal and demographic factors on the incidence of acute pancreatitis.

News image

The incidence of acute pancreatitis has increased sharply in many European countries and the USA in recent years.

Dr Roberts and colleagues from the United Kingdom evaluated trends in incidence and mortality for acute pancreatitis in Wales, UK,.

The researchers assessed how incidence may be linked to factors including social deprivation, seasonal effects and alcohol consumption.

The team linked inpatient, mortality and primary care data for 10,589 hospitalized cases of acute pancreatitis between 1999 and 2010.

The incidence of acute pancreatitis was 30 per 100,000 population overall, mortality was 6% at 60 days.

The researchers observed that the incidence increased significantly from 27 per 100, 000 in 1999 to 36 in 2010, with little trend in mortality.

Incidence was about 2 times higher among the most deprived quintile of patients
Alimentary Pharmacology & Therapeutics

The doctors found the largest increases in incidence were among women aged <35 years and men aged 35–44 and 45–54.

Incidence was about 2 times higher among the most deprived quintile of patients compared with the most affluent.

Acute pancreatitis was increased significantly during the Christmas and New Year weeks by 48% for alcoholic aetiology, but not for gallstone etiology.

Alcoholic admissions were increased with higher consumption of spirits and beer, but not wine.

Dr Roberts' team concludes, "The study shows an elevated rate of alcoholic acute pancreatitis during the Christmas and New Year period."

"Acute pancreatitis continues to rise, most rapidly for young women, while alcoholic acute pancreatitis is linked strongly with social deprivation."

Aliment Pharmacol & Ther 2013: 38(5) 539–548
02 September 2013

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