Excessive alcohol use has been reported to be responsible for 80,000 annual deaths in the United States.
However, the exact cause of death related to the excessive use of alcohol has not been fully explored.
Dr Trimble and colleagues from Virginia, USA assessed the effect of alcoholic liver disease on all-cause, liver-related and cardiovascular mortality using population-based data.
|Mortality follow-up data were available for a median of 178 months|
|Alimentary Pharmacology & Therapeutics|
Data were obtained from the Third National Health and Nutrition Examination Survey Linked Mortality Files.
Alcohol consumption was estimated as grams per day.
The researchers used multivariate Cox proportional hazards model to assess the effects of alcoholic liver diesease on follow-up time to mortality from all causes, cardiovascular disease and liver disease.
A total of 8,306 participants were included.
The team found that mortality follow-up data were available for a median time of 178 months.
The researchers found that participants with alcoholic liver disease had increased risk for liver-related mortality, but not for overall mortality or cardiovascular mortality.
Dr Trimble's team concludes, "Alcoholic liver disease increases the risks for liver-related mortality but not for cardiac or overall mortality."