Help
Subscribe


GastroHep.com - the global online resource for all aspects of gastroenterology, hepatology and endoscopy

 12 February 2016

Advanced search
GastroHep.com - the global online resource for all aspects of gastroenterology, hepatology and endoscopy Profile of Roy Pounder

Home

News  
Journals
Review Articles
Slide Atlas
Video Clips
Online Books
Advanced Digestive Endoscopy
Classical Cases
Conference Diary
PubMed
International GH Links
USA GH Links
National GH Links
National GI Societies
Other Useful Links




Emails on Gastroenterology and Hepatology
the National AIDS Treatment Advocacy Project
Visit the gastroenterology section of the EUMS

News

Hepatitis C genotype predicts the risk of mortality in individuals co-infected with HIV

Does hepatitis C viremia or genotype predict the risk of mortality in individuals co-infected with HIV, reports the latest Journal of Hepatology.

News image

The influence of hepatitis C virus-RNA levels and genotype on hepatitis C virus disease progression is not well studied.

The prognostic value of these markers was investigated in human immunodeficiency virus/hepatitis C virus co-infected individuals from the EuroSIDA cohort.

Dr Jurgen Rockstroh and colleagues from Germany undertook EuroSIDA as a prospective cohort of 18,295 HIV-1 infected patients in 105 centres across Europe, Israel, and Argentina.

All subjects with known hepatitis C virus antibody status were enrolled in the present study.

Patients with detectable HCV-RNA had similar incidence of non-liver-related death
Journal of Hepatology

The team noted that 4044 patients had detectable anti-hepatitis C antibody.

After adjustment, anti-hepatitis C virus antibody patients had an increased incidence of liver-related death compared to hepatitis C virus antibody− individuals.

Information on Hepatitis C virus-RNA was available for 2709 hepatitis C virus antibody positive patients, and 2010 were hepatitis C virus-RNA positive.

Of 1907 patients with measured hepatitis C genotype, 1008, 62 , 567 , and 270 were infected with genotype 1, 2, 3 and 4, respectively.

The research team  observed that patients with detectable hepatitis C virus-RNA had similar incidence of non-liver-related death, but higher incidence of liver-related death compared to hepatitis C virus antibody positive aviremic patients, respectively.

In patients with hepatitis C virus viremia, hepatitis C virus-RNA levels and hepatitis C virus genotype did not influence the risk of non-liver-related death or liver-related death.

Dr Rockstroh's team concluded, "Hepatitis C virus seropositive human immunodeficiency virus patients had a 9-fold increased risk of liver related death compared to patients who were hepatitis C seronegative."

"Risk of death from any cause or liver related death was not influenced by level of hepatitis C virus viremia or hepatitis C virus genotype."

J Hepatol 2013 : 59(2): 213-220
26 July 2013

Go to top of page Email this page Email this page to a colleague

 12 February 2016 
Colorectal cancer after negative signoidoscopy
 12 February 2016 
Genetic factors and response to glucocorticoids in IBD
 12 February 2016 
Tobacco smoking and the natural history of Crohn’s
 11 February 2016 
Colorectal surgery training
 11 February 2016 
Liver disease unique to pregnancy
 11 February 2016 
Serous cystic neoplasm 
 10 February 2016 
NAFLD in Veterans in the USA
 10 February 2016 
Rectosigmoidoscopy vs colonoscopy in ulcerative colitis
 10 February 2016 
Liver cancer and primary biliary cirrhosis
 09 February 2016 
Bowel preparation for colonoscopy screening
 09 February 2016 
Eosinophilic esophagitis and parental allergies
 09 February 2016 
Cancer-specific prognosis in octogenarians with colorectal cancer
 08 February 2016 
Cancelled colonoscopy appointments
 08 February 2016 
Cognitive function in Crohn's disease
 08 February 2016 
Immunity in the human gut
 05 February 2016 
Treatment for ileal pouch-anal anastomosis for Crohn’s colitis
 05 February 2016 
Helicobacter cinaedi bacteremia
 05 February 2016 
Methotrexate and remission in ulcerative colitis
 04 February 2016 
Diabetes and liver cancer
 04 February 2016 
Colorectal cancer screening
 04 February 2016 
H. pylori and coronary heart disease 
 03 February 2016 
Acute diverticulitis and IBS 
 03 February 2016 
Microbiota of the colonic mucosa and chronic constipation
 03 February 2016 
Guidelines for chronic pancreatitis
 02 February 2016 
Ramosetron and IBS-diarrhea
 02 February 2016 
IBD emergency department visits
 02 February 2016 
Probiotics for H. pylori management
 01 February 2016 
Managing HBV in pregnancy
 01 February 2016 
Depressive symptoms in IBD 
 01 February 2016 
Obesity and hepatocellular carcinoma risk
 29 January 2016 
Colorectal cancer after colonoscopy
 29 January 2016 
Acute diverticulitis in immunosuppressed patients
 29 January 2016 
Vitamin D and colorectal cancer risk
 28 January 2016 
Tissue anti-TNF drug levels and IBD
 28 January 2016 
First line treatment of H. pylori infection
 28 January 2016 
Tetracycline for rosacea increases the risk of IBD
 27 January 2016 
Steroids in children with Crohn's
 27 January 2016 
Self-management IBS program 
 27 January 2016 
Human gut microbiome in IBD 
 26 January 2016 
Smoking and symptomatic diverticular disease
 26 January 2016 
Step-down therapy in PPI-responsive esophageal eosinophilia 
 26 January 2016 
Diet and IBD risk
 25 January 2016 
IBD monitoring using smartphones
 25 January 2016 
Self-management IBS program
 25 January 2016 
Colorectal cancer after a negative screening sigmoidoscopy
 22 January 2016 
Length of Barrett's and cancer
 22 January 2016 
Psychosocial interventions and alcohol abstinence in chronic liver disease
 22 January 2016 
Helicobacter pylori antibiotic resistance
 21 January 2016 
Increasing adenoma detection rate during colonoscope withdrawal
 21 January 2016 
Microscopic colitis current concepts
 21 January 2016 
Statins as a management strategy for constipation 
 20 January 2016 
Health status after bariatric surgery
 20 January 2016 
Hep E infection in West Africa
 20 January 2016 
Preventing endoscopic bacterial transmission
 19 January 2016 
PPIs and phlebotomy in hereditary hemochromatosis
 19 January 2016 
Predicting liver cirrhosis in Hep C
 19 January 2016 
Frozen vs fresh fecal microbiota transplantation
 18 January 2016 
Hospitalization for diverticulitis in the USA
 18 January 2016 
H. pylori and gastric cancer across Europe
 18 January 2016 
Enteral nutrition in children with Crohn's

Blackwell Publishing


GastroHep.com is a Blackwell Publishing registered trademark
© 2016 Wiley-Blackwell and GastroHep.com and contributors
Privacy Statement
Disclaimer
About Us