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Vegetables, fruit and risk of non-gallstone-related acute pancreatitis

Vegetables, fruit and risk of non-gallstone-related acute pancreatitis: a population-based prospective cohort study

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Dr Viktor Oskarsson and colleagues from Sweden performed a population-based prospective cohort of 80,019 women and men, aged 46–84 years.

The patients completed a food-frequency questionnaire at baseline and was followed up for incidence of non-gallstone-related acute pancreatitis from 1998 to 2009.

Participants were categorized into quintiles according to consumption of vegetables and consumption of fruit.

The research team identified 320 incident cases with non-gallstone-related acute pancreatitis during 12 years of follow-up.

After adjustment for potential confounders, the team observed a significant inverse linear dose–response association between vegetable consumption and risk of non-gallstone-related acute pancreatitis.

The team found that every 2 additional servings per day were associated with a 17% risk reduction.

Every 2 additional servings per day were associated with a 17% risk reduction
Gut

The researchers found that among participants consuming more than 1 drink of alcohol per day, and among those with body mass index of 25 kg/m2.

The relative risk for the highest compared with the lowest quintile of vegetable consumption was 0.3 and 0.5, respectively.

Fruit consumption was not significantly associated with the risk of non-gallstone-related acute pancreatitis; the relative risk comparing extreme quintiles of consumption was 1.20.

The Oskarsson's commented, "Vegetable consumption, but not fruit consumption, may play a role in the prevention of non-gallstone-related acute pancreatitis."

Gut 2013; 62: 1187-1192
17 July 2013

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