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 11 February 2016

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News

Western dietary pattern is associated with NAFLD in adolescence

A study in this month's issue of the American Journal of Gastroenterology reports that the Western dietary pattern is prospectively associated with nonalcoholic fatty liver disease in adolescence.

News image

Poor dietary habits have been implicated in the development of nonalcoholic fatty liver disease (NAFLD).

However, little is known about the role of specific dietary patterns in the developmentt of NAFLD.

Dr Wendy Oddy and colleagues from Australia examined prospective associations between dietary patterns and NAFLD in a population-based cohort of adolescents.

Participants in the Western Australian Pregnancy Cohort (Raine) Study completed a food frequency questionnaire at 14 years and had liver ultrasound at 17 years.

The research team identified healthy and Western dietary patterns using factor analysis, and all participants received a z-score for these patterns.

Prospective associations between the dietary pattern scores, and risk of NAFLD were analyzed using multiple logistic regression.

NAFLD was present in 15% of adolescents
American Journal of Gastroenterology

The researchers found that NAFLD was present in 15% of adolescents.

A higher Western dietary pattern score at 14 years was associated with a greater risk of NAFLD at 17 years, although these associations were no longer significant after adjusting for body mass index at 14 years.

The research team found that a healthy dietary pattern at 14 years appeared protective against NAFLD at 17 years in centrally obese adolescents.

The team noted that a Western dietary pattern was associated with an increased risk of NAFLD.

Dr Oddy's team commented, "A Western dietary pattern at 14 years in a general population sample was associated with an increased risk of NAFLD at 17 years, particularly in obese adolescents."

"In centrally obese adolescents with NAFLD, a healthy dietary pattern may be protective, whereas a Western dietary pattern may increase the risk."

Am J Gastroenterol 2013; 108: 778–785
23 May 2013

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