Help
Subscribe


GastroHep.com - the global online resource for all aspects of gastroenterology, hepatology and endoscopy

 25 September 2016

Advanced search
GastroHep.com - the global online resource for all aspects of gastroenterology, hepatology and endoscopy Profile of Roy Pounder

Home

News  
Journals
Review Articles
Slide Atlas
Video Clips
Online Books
Advanced Digestive Endoscopy
Classical Cases
Conference Diary
PubMed
International GH Links
USA GH Links
National GH Links
National GI Societies
Other Useful Links




Emails on Gastroenterology and Hepatology
the National AIDS Treatment Advocacy Project
Visit the gastroenterology section of the EUMS

News

Anti-tumor necrosis factor associated with infections after abdominal surgery in Crohn's

Anti-tumor necrosis factor therapy is associated with infections after abdominal surgery in Crohn's disease patients, reports April's issue of the American Journal of Gastroenterology.

News image

Anti-tumor necrosis factor (anti-TNF) therapy effects on postoperative complications in Crohn's disease patients are unclear.

Dr Ali Syed and colleagues performed a retrospective cohort to clarify this relationship.

The team followed Crohn's disease patients at a referral center between 2004 and 2011 who underwent abdominal surgery were identified.

Postoperative complications were compared in patients exposed and unexposed to Anti-tumor necrosis factor  8 weeks preoperatively.

The team of doctors reported that demographics, surgical history, comorbidities, corticosteroid and immunomodulator use, Montreal classification, operative details, and preoperative nutritional status were assessed.

The research team measured the independent effect of preoperative anti-tumor necrosis factor on postoperative complications.

The research team noted that overall, 325 abdominal surgeries were performed, and 150 received anti-tumor necrosis factor  8 weeks before surgery.

The anti-TNF group developed overall infectious  more frequently
American Journal of Gastroenterology

The anti-tumor necrosis factor group developed overall infectious, and a trend toward surgical site complications more frequently.

The team of doctors assessed that major postoperative and intra-abdominal septic complications did not differ between groups.

Multivariable analysis showed that preoperative anti-tumor necrosis factor was an independent predictor of overall infectious.

Dr Syed's team commented "In a tertiary referral center, use of anti-tumor necrosis factor therapy in Crohn's disease patients 8 weeks or less before intestinal resection or any intra-abdominal surgery was independently associated with increases in infectious and surgical complications."

Am J Gastroenterol 2013; 108: 583–593
29 April 2013

Go to top of page Email this page Email this page to a colleague

 23 September 2016 
Exercise for NAFLD
 23 September 2016 
BMI history and fatty liver
 23 September 2016 
Sleep quality in nonalcoholic cirrhotic patients
 22 September 2016 
Predicting small-bowel Crohn’s disease
 22 September 2016 
Technology vs intervention for weight loss
 22 September 2016 
Colectomy outcomes for ulcerative colitis
 21 September 2016 
Cardiopulmonary exercise testing in liver transplant candidates
 21 September 2016 
Employment status and IBD
 21 September 2016 
Patients vs providers on nutrition in IBD
 20 September 2016 
Improving healthcare systems for viral Hepatitis
 20 September 2016 
GI benefits of COX-2 selective inhibitors
 20 September 2016 
Predicting relapse in Crohn's
 19 September 2016 
Prevalence of esophageal cancer in Barrett's
 19 September 2016 
Fecal microbiota transplantation and CDI in IBD
 19 September 2016 
Antibiotic resistance in Helicobacter pylori
 16 September 2016 
Low-residue diet before colonoscopy and bowel cleansing
 16 September 2016 
Genome-wide association in gastric cancer
 16 September 2016 
H. pylori in children with asthma
 15 September 2016 
Improving survival in cholangitis-associated septic shock
 15 September 2016 
Colorectal cancer survival and hospital volumes
 15 September 2016 
Primary sclerosing cholangitis and IBD
 14 September 2016 
Intestinal malabsorption and olmesartan
 14 September 2016 
Infection reduction strategy after colorectal resection
 14 September 2016 
Predicting long-term infliximab use in Crohn's
 13 September 2016 
Predicting survival in refractory celiac disease
 13 September 2016 
Cancer risk stratification in Barrett’s
 13 September 2016 
Screening vs non-screening colonoscopy
 12 September 2016 
Screening in familial colorectal cancer
 12 September 2016 
Metformin improves survival in pancreatic ductal cancer
 12 September 2016 
Consent guidelines for GI endoscopy procedures
 09 September 2016 
Development of IBS
 09 September 2016 
Safe and effective treatment for NASH
 09 September 2016 
Scale for stool measurement in diarrhea-IBS
 08 September 2016 
Prognostic factors for infliximab in Crohn's
 08 September 2016 
Chronic Hep B vs chronic Hep C and mortality
 08 September 2016 
Hematological malignancies in IBD
 07 September 2016 
IBD relapse during pregnancy
 07 September 2016 
New treatments for ulcerative colitis
 07 September 2016 
Alternative to nucleic acid testing in HCV
 06 September 2016 
Endoscopy clinic no-shows
 06 September 2016 
Risk of infection after elective colorectal surgery
 06 September 2016 
EHealth technologies in IBD
 05 September 2016 
Esophageal impedance monitoring
 05 September 2016 
Family history and IBD clinical course
 05 September 2016 
Biomarker for IBD and GI cancer
 02 September 2016 
Dietary carbohydrate intake, insulin resistance and GERD 
 02 September 2016 
Postpolypectomy bleeding in the colorectum
 02 September 2016 
Postop recurrence of Crohn's
 01 September 2016 
Prognostic test for liver transplants
 01 September 2016 
Recovery after colorectal surgery in elderly patients
 01 September 2016 
Obesity and post-ERCP pancreatitis
 30 August 2016 
NAFLD and carotid atherosclerosis
 30 August 2016 
Quality improvement program after colorectal surgery
 30 August 2016 
Gut microbial diversity in smokers with Crohn's
 29 August 2016 
Reducing Hep B-related HCC
 29 August 2016 
Hep B immunization of infants for liver cancer
 29 August 2016 
Risk factor for post-ERCP pancreatitis
 26 August 2016 
Reasons for premature surveillance colonoscopy
 26 August 2016 
Celiac disease therapeutics
 26 August 2016 
Bleeding after endoscopic dissection-induced gastric ulcers

Blackwell Publishing


GastroHep.com is a Blackwell Publishing registered trademark
© 2016 Wiley-Blackwell and GastroHep.com and contributors
Privacy Statement
Disclaimer
About Us