Diet could affect risk for esophageal and gastric cancers, but associations have been inconsistent.
The diet is complex, so studies of dietary patterns, rather than studies of individual foods, might be more likely to identify cancer risk factors.
Dr Wen-Qing Li reported that there is limited research on index-based dietary patterns and esophageal and gastric cancers.
We prospectively evaluated associations between the Healthy Eating Index-2005 and alternate Mediterranean Diet scores and risk of esophageal and gastric cancers.
The doctors assessed that they analyzed data from 494,968 participants in the National Institutes of Health (NIH)-AARP Diet and Health study, in which AARP members completed a self-administered baseline food frequency questionnaire between 1995 and 1996.
|Mediterranean Diet scores were not associated with gastric cardia adenocarcinomas|
|Clinical Gastroenterology and Hepatology|
Their answers were used to estimate scores for each index.
The reseaerch team examined that during the follow-up period, participants developed 215 esophageal squamous cell carcinomas, 633 esophageal adenocarcinomas, 453 gastric cardia adenocarcinomas, and 501 gastric non-cardia adenocarcinomas.
Higher scores from the Healthy Eating Index-2005 were associated with a reduced risk of esophageal squamous cell carcinomas and esophageal adenocarcinomas.
The doctors observed an inverse association between esophageal squamous cell carcinomas, but not , and higher alternate Mediterranean Diet score.
Healthy Eating Index-2005 and alternate Mediterranean Diet scores were not significantly associated with gastric cardia or noncardia adenocarcinomas.
Dr Wen-Qing Li's team commented "Using data collected from 1995 through 2006 from the National Institutes of Health Diet and Health Study,alternate Mediterranean Diet scores were inversely associated with risk for esophageal cancers—
particularly esophageal squamous cell carcinomas."
"Adherence to dietary recommendations might help prevent esophageal cancers."