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News

Racial and ethnic variation in the incidence of small-bowel cancer subtypes in the USA

The latest issue of the Diseases of the Colon & Rectum reports racial and ethnic variation in the incidence of small-bowel cancer subtypes in the United States.

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Small-bowel cancer is uncommon and, accordingly, little is known about the epidemiology of this malignancy, especially by race and subtype.

Dr Marc Goodman and colleagues described the distribution of small-bowel cancer in the United States by demographic, pathological, and clinical features.

This study was retrospective in design.

The team used data from 26 population-based cancer registries in the United States from 1995 to 2008.

Patients diagnosed with small-bowel cancer were included.

The research team's primary outcomes measured were race- and histology-specific incidence of small-bowel cancer.

A total of 56,223 men and women diagnosed with small-bowel cancer were identified.

The doctors examioned that the overall age-adjusted incidence rates for small-bowel cancer were 26 in men, and 18 in women.

Rates of small-bowel cancer were 24% lower in Hispanic men
Diseases of the Colon & Rectum

Neuroendocrine tumors were the most common histological types of small-bowel cancer in men and women, followed by carcinoma, lymphoma, and sarcoma.

The doctors assessed that in comparison with whites, the rate of small-bowel cancer was 42% greater in black men, 46% greater in black women, 34% lower in Asian-Pacific Islander men, and 37% lower in Asian-Pacific Islander women.

Rates of small-bowel cancer were 24% lower in Hispanic men, and 15% lower in Hispanic women than rates in non-Hispanics.

The team of doctors reported that the excess of small-bowel cancer in blacks and the deficit in Asian-Pacific Islanders were attributable mainly to the incidence of adenocarcinoma and carcinoid tumors.

The incidence of GI stromal tumor was significantly higher among Asian-Pacific Islanders.

Dr Goodman's team commented, "This is one of the largest studies of small-bowel cancer to date."

"These cancer registry data showed substantial racial and ethnic variation in the incidence of histological subtypes of small-bowel malignancy that suggest possible etiologic diversity and/or disparities in detection."

Dis Colon Rectum 2013: 56(4): 441-448
12 April 2013

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