Help
Subscribe


Submit Videos to GastroHep Read For FREE - Our full range of review articles
GastroHep.com - the global online resource for all aspects of gastroenterology, hepatology and endoscopy
GastroHep.com - the global online resource for all aspects of gastroenterology, hepatology and endoscopy Profile of Guido Tytgat Profile of Pete Peterson Profile of Peter Cotton Profile of Roy Pounder

Home

News  
Journals
Review Articles
Slide Atlas
Video Clips
Online Books
Advanced Digestive Endoscopy
Classical Cases
Conference Diary
PubMed
International GH Links
USA GH Links
National GH Links
National GI Societies
Other Useful Links




Emails on Gastroenterology and Hepatology
the National AIDS Treatment Advocacy Project
Visit the gastroenterology section of the EUMS

News

Offering people a choice for colorectal cancer screening

A study in the latest issue of Gut examines the effect of offering people a choice for colorectal cancer screening.

News image

Dr Carlo Senore and colleagues from Italy assessed the population coverage and diagnostic yield of offering an immunochemical fecal occult blood test to non-responders to a flexible sigmoidoscopy invitation.

A cohort study conducted in a population-based colorectal cancer screening program.

In this program, eligible men and women aged 58 or 60 are invited, with a personal letter signed by their general practitioner, to undergo an flexible sigmoidoscopy.

Bowel preparation is limited to a single enema self-administered at home.
 
Subjects in whom one distal polyp more than 5 mm or at least one adenoma is detected at flexible sigmoidoscopy are referred for colonoscopy.

19% underwent an immunochemical fecal occult blood test
Gut

The team reported that people who do not respond to the invitation to undergo an flexible sigmoidoscopy are invited to have an immunochemical fecal occult blood test.

Attendance rate and neoplasia yield were analyzed in 4 consecutive birth cohorts.

The research team found that overall participation rate for the flexible sigmoidoscopy invitation was 39% in Verona, and 30% in Turin.

Of the eligible non-responders to the flexible sigmoidoscopy invitation, 19% underwent an immunochemical fecal occult blood test.

As a result, the team reported that the proportion of people undergoing screening by flexible sigmoidoscopy or immunochemical fecal occult blood test was 55% in Verona, and 39% in Turin, with no gender differences in either center.

Immunochemical fecal occult blood test detected 8% of all advanced adenomas, and 20% of all colorectal cancers diagnosed at screening.

Dr Senore's team concludes, "A strategy involving the sequential offer of flexible sigmoidoscopy, and immunochemical fecal occult blood test is a feasible and efficient approach."

"Immunochemical fecal occult blood test in people not attending for flexible sigmoidoscopy increases screening uptake and detection of advanced adenomas and colorectal cancers."

Gut 2013; 62: 735-740 
10 April 2013

Go to top of page Email this page Email this page to a colleague

 30 October 2014

Advanced search
 30 October 2014 
Cirrhosis in women
 30 October 2014 
Costs in newly diagnosed patients with chronic constipation
 30 October 2014 
Constipation and colorectal cancer
 29 October 2014 
IBS in primary care
 29 October 2014 
Sensorimotor activity in functional dyspepsia
 29 October 2014 
Quality of life after infection with E. coli
 28 October 2014 
Increased bile acid synthesis in IBS-diarrhea
 28 October 2014 
Risk factor for smaller final height in Crohn's
 28 October 2014 
Successful radiofrequency ablation for Barrett’s
 27 October 2014 
Celiac disease and type 1 diabetes
 27 October 2014 
Gluten awareness among chefs
 27 October 2014 

PPI-responsive esophageal eosinophilia

 24 October 2014 
Olmesartan-associated enteropathy
 24 October 2014 
Opioid use in IBD
 24 October 2014 
NSAIDs and Barrett's risk
 23 October 2014 
Outcomes in hospitalized patients with GI bleeding
 23 October 2014 
Thiopurines and colorectal cancer risk in IBD
 23 October 2014 
Advancing the field of functional GI disorders
 22 October 2014 
Early-TIPSS placement prevents rebleeding
 22 October 2014 
Liver fibrosis prognostic biomarkers in type-2 diabetes
 22 October 2014 
H pylori eradication with multiple drug resistance
 21 October 2014 
Alcohol and Barrett's
 21 October 2014 
Scoring systems for critically ill cirrhotic patients
 21 October 2014 
Aspirin and NAFLD
 20 October 2014 
Drug resistant H pylori eradication
 20 October 2014 
Adalimumab in secondary loss of response in Crohn's
 20 October 2014 
Omega-3 and colorectal cancer
 17 October 2014 
Colorectal testing utilization
 17 October 2014 
Tumor necrosis factor-alpha inhibitors and pregnancy in IBD
 17 October 2014 
Fecal microbiota composition in postinfectious IBS
 16 October 2014 
Risk of Barrett's esophagus
 16 October 2014 
Aspirin tablets and colorectal tumours
 16 October 2014 
Economic impact of IBS
 15 October 2014 
Preparation for surgery in Crohn's
 15 October 2014 
Achieving competency at colonoscopy
 15 October 2014 
Bowel preparations
 14 October 2014 
Colorectal testing utilization in commercially insured US adults
 14 October 2014 
Sustained response to infliximab
 14 October 2014 
IBD management during pregnancy
 13 October 2014 
Predicting PPI response in GERD-related cough
 13 October 2014 
Probiotics in IBS
 13 October 2014 
Use of azathioprine in IBD
 10 October 2014 
Liver injury from herbals and dietary supplements
 10 October 2014 
NAFLD in the Veterans Administration population
 10 October 2014 
Predictors for cecal insertion time
 09 October 2014 
Methotrexate-related liver disease and metabolic syndrome
 09 October 2014 
Biomarkers of acetaminophen overdose patients
 09 October 2014 
Postoperative adhesions in digestive surgery
 08 October 2014 
Gluten introduction in high risk children
 08 October 2014 
Vitamin D and HCC
 08 October 2014 
Feeding intervention in celiac disease infants
 07 October 2014 
Infliximab in pediatric perianal Crohn's
 07 October 2014 
Omega-3 and NAFLD
 07 October 2014 
Endoscopic submucosal dissection in the colorectum 
 06 October 2014 
Clinical indications for computed tomographic colonography
 06 October 2014 
Certolizumab pegol in the treatment of Crohn's
 06 October 2014 
Costs of telaprevir therapy for Hep C
 03 October 2014 
Depression and liver transplantation
 03 October 2014 
Orange juice intake during bowel preparation
 03 October 2014 
HCV and diabetes

Blackwell Publishing


GastroHep.com is a Blackwell Publishing registered trademark
© 2014 Wiley-Blackwell and GastroHep.com and contributors
Privacy Statement
Disclaimer
About Us