Help
Subscribe


Submit Videos to GastroHep Read For FREE - Our full range of review articles
GastroHep.com - the global online resource for all aspects of gastroenterology, hepatology and endoscopy
GastroHep.com - the global online resource for all aspects of gastroenterology, hepatology and endoscopy Profile of Guido Tytgat Profile of Pete Peterson Profile of Peter Cotton Profile of Roy Pounder

Home

News  
Journals
Review Articles
Slide Atlas
Video Clips
Online Books
Advanced Digestive Endoscopy
Classical Cases
Conference Diary
PubMed
International GH Links
USA GH Links
National GH Links
National GI Societies
Other Useful Links




Emails on Gastroenterology and Hepatology
the National AIDS Treatment Advocacy Project
Visit the gastroenterology section of the EUMS

News

Colorectal cancer screening interval after negative colonoscopy

The latest issue of Surgical Endoscopy investigaates the correct screening interval for colorectal cancer after negative colonoscopy.

News image

Despite the high sensitivity of screening colonoscopy, polyps and cancers can still go undetected.

With the polyp-to-cancer transformation cycle averaging 710 years, present guidelines recommend repeat colonoscopy within 10 years after negative screening.

However, not all colorectal malignancies follow this decade-long progression.

Dr Steven Nakao and colleagues evaluated the incidence and pathology of colorectal cancers following a previous negative screening colonoscopy.

Records of patients who underwent a colectomy at our institution, from 1998 to 2009, were reviewed retrospectively.

The researchers reported that a total of 1,784 patient records were screened using exclusion criteria for inclusion in this study.

Group 1 included patients with a negative colonoscopy within the previous 5 years.

Group 2 included patients without a previous colonoscopy or with a previous colonoscopy more than 5 years prior.

Group 1 patients were evaluated by colonoscopy for anemia, diverticulitis, signs of obstruction, and bleeding.

Age, tumor location, operation performed, and pathology findings were recorded.

The team of researchers assessd that the χ2 test and paired t test were used for statistical analysis.

A total of 233 patients were included in this study.

18% developed colorectal cancer
Surgical Endoscopy

Group 1 contained 43 patients with a mean age of 73 years.

Group 2 had 190 patients with a mean age of 68 years.

The team of doctors noted that group 1 consisted of 18 male and 25 female patients, and Group 2 included 94 male and 96 female patients.

Both groups were further classified into age categories including 50 years, 5080 years, and 80 years.

The research team noted that 18% of the total study population had newly discovered colorectal cancer within a 5-year colonoscopy screening period.

There were no significant differences in the distribution of the T and N stages between the 2 groups, and no statistically significant differences when the rate of lymphovascular invasion and perineural invasion were compared.

Within 5 years, 18% developed colorectal cancer.

Dr Nakao's team commented "Most of these malignancies were found within the 5080-year age group and located predominantly in the right colon and distally in the sigmoid and rectum."

"While distal cancers may be visualized by flexible sigmoidoscopy, those located more proximally may be missed, necessitating the need for a full colonoscopy."

"Although staging was similar between the two groups, Group 1 tumors were less aggressive despite having appeared within 5 years."

"As a result of our incidence of colorectal cancer within a 5-year interval, a shorter period for routine colonoscopy may be considered."

Surgical Endoscopy 2013: 3(27): 768-773
01 April 2013

Go to top of page Email this page Email this page to a colleague

 30 January 2015

Advanced search
 30 January 2015 
HIV-associated NAFLD and primary NAFLD
 30 January 2015 
Narcotic use in children with IBD
 30 January 2015 
Removal of rectal neoplasms
 29 January 2015 
Pyloric compliance in gastroparesis
 29 January 2015 
Gastric cancer in peptic ulcer disease
 29 January 2015 
Genetics and risk of Barrett's
 28 January 2015 
Metabolic syndrome in celiac disease
 28 January 2015 
Remission in Crohn's disease
 28 January 2015 
Surgery and quality of life in rectal cancer
 27 January 2015 
Outcomes for liver transplantation
 27 January 2015 
Psychological distress and fecal composition in IBS
 27 January 2015 
Risk of upper GI cancers in GERD
 26 January 2015 
Breath analysis for IBD
 26 January 2015 
Fecal microbiota transplantation
 26 January 2015 
Antidepressants and GERD
 23 January 2015 
Liver transplant outcomes
 23 January 2015 
Breath analysis in IBD
 23 January 2015 
Fecal microbiota transplantation
 22 January 2015 
NASH and lipid improvements
 22 January 2015 
NAFLD and NASH with psoriasis
 22 January 2015 
Predicting outcomes in HCV-related advanced liver disease
 21 January 2015 
Colon capsule versus CT colonography
 21 January 2015 
Barrett's esophagus screening in the community
 21 January 2015 
Portal vein obstruction
 20 January 2015 
Modulating mucosal damage in Crohn's
 20 January 2015 
Novel techniques for Barrett's screening
 20 January 2015 
Food intolerance
 19 January 2015 
Treatment of fecal incontinence
 19 January 2015 
Hepatic cyst infection
 19 January 2015 
Risk of IBS among relatives
 16 January 2015 
Colorectal cancer screening uptake
 16 January 2015 
NAFLD and NASH in patients with psoriasis
 16 January 2015 
Fecal incontinence
 15 January 2015 
Coffee intake and liver disease
 15 January 2015 
NAFLD in primary care practice
 15 January 2015 
Management of univestigated dyspepsia
 14 January 2015 
Missed colorectal cancers after colonoscopy with polypectomy
 14 January 2015 
Inflixmab response in Crohn's
 14 January 2015 
Statins and liver injury in chronic liver disease
 13 January 2015 
Cytomegalovirus in IBD
 13 January 2015 
Helicobacter-negative gastritis
 13 January 2015 
Hep B vaccine in IBD
 12 January 2015 
Survival in Hep B virus-related hepatocellular carcinoma
 12 January 2015 
Relapse of Crohn's disease after surgery
 12 January 2015 
Late liver metastases of colorectal cancer
 09 January 2015 
Fecal microbiota transplantation for refractory Crohn's
 09 January 2015 
Hypercoagulability after liver resection
 09 January 2015 
Naps and gastroesophageal reflux vs nocturnal sleep
 08 January 2015 
Post-infectious functional dyspepsia
 08 January 2015 
Diagnosis of liver iron overload
 08 January 2015 
Digestive tract damage in Crohn's disease
 07 January 2015 
Early-onset colorectal cancer
 07 January 2015 
SSRIs for noncardiac chest pain
 07 January 2015 
SSRIs and upper GI bleeds
 06 January 2015 
Detection of inflammation in Crohn's
 06 January 2015 
Leptin and early-onset extreme obesity
 06 January 2015 
Goals of IBD treatment
 19 December 2014 
Thiopurine treatment and colectomy in ulcerative colitis
 19 December 2014 
Idiopathic inflammatory demyelinating disease in IBD
 19 December 2014 
Colorectal cancer risk for first-degree relatives

Blackwell Publishing


GastroHep.com is a Blackwell Publishing registered trademark
© 2015 Wiley-Blackwell and GastroHep.com and contributors
Privacy Statement
Disclaimer
About Us