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News

Risk factors of ischemic heart disease in patients with celiac disease

A study published ahead of print in Alimentary Pharmacology & Therapeutics characterized risk factors of ischamic heart disease in patients with celiac disease.

News image

Dr Emilsson and colleagues from Sweden characterised ischemic heart disease according to celiac disease status.

Data on duodenal or jejunal biopsies were collected in 2006–2008 from all 28 pathology departments in Sweden, and were used to define celiac disease.

The research team used the Swedish cardiac care register SWEDEHEART to identify ischemic heart disease, and obtained data on clinical status and risk factors at time of first myocardial infarction for this case-only comparison.

The team of doctors compared celiac disease patients with general population reference individuals.

The research team identified 1075 celiac disease patients, and 4142 reference individuals with subsequent ischemic heart disease.

Celiac disease patients had less extensive coronary artery disease at angiography
Alimentary Pharmacology & Therapeutics

The research team found that celiac disease patients with myocardial infarction had lower body mass index and cholesterol values, and were less likely to be active smokers than reference individuals with myocardial infarction.

The team noted that celiac disease patients had less extensive coronary artery disease at angiography; but there was no difference in the proportions of celiac disease patients with positive biochemical markers of myocardial infarction.

Dr Emilsson's team commented, "Despite evidence of an increased risk of ischemic heart disease and higher cardiovascular mortality, celiac disease patients with ischemic heart disease have a more favorable cardiac risk profile compared with ischemic heart disease in reference individuals."

Aliment Pharmacol Ther 2013: DOI: 10.1111/apt.12271
01 April 2013

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