Help
Subscribe


GastroHep.com - the global online resource for all aspects of gastroenterology, hepatology and endoscopy

 25 July 2016

Advanced search
GastroHep.com - the global online resource for all aspects of gastroenterology, hepatology and endoscopy Profile of Roy Pounder

Home

News  
Journals
Review Articles
Slide Atlas
Video Clips
Online Books
Advanced Digestive Endoscopy
Classical Cases
Conference Diary
PubMed
International GH Links
USA GH Links
National GH Links
National GI Societies
Other Useful Links




Emails on Gastroenterology and Hepatology
the National AIDS Treatment Advocacy Project
Visit the gastroenterology section of the EUMS

News

Biliary complications after living and deceased donor liver transplantation

The latest issue of Liver Transplantation reports on the development, management, and resolution of biliary complications after living and deceased donor liver transplantation.

News image

Adult recipients of living donor liver transplantation have a higher incidence of biliary complications than recipients of deceased donor liver transplantation.

Dr Michael Zimmerman and colleagues analyzed the management and resolution of posttransplant biliary complications, and investigated the comparative effectiveness of interventions in living donor liver transplantation and deceased donor liver transplantation recipients. 

Patients participating in this trial were enrolled in the National Institutes of Health–sponsored Adult-to-Adult Living Donor Liver Transplantation Cohort Study and underwent liver transplantation at 8 centers between 1998 and 2006.

The trial was also funded by research grants from Schering-Plough through a cooperative research and development agreement with the National Institute of Diabetes and Digestive and Kidney Diseases/National Institutes of Health, and through a clinical trial agreement between Ortho-Biotech and the National Institute of Diabetes and Digestive and Kidney Diseases/National Institutes of Health.

The research team reported that additional support was provided by the Health Resources and Services Administration and the American Society of Transplant Surgeons.

The numbers, procedure types, and times to resolution were compared for living donor liver transplantation and deceased donor liver transplantation  recipients.

The team of doctors reported that the posttransplant biliary complications occurred in 47 of the 189 deceased donor liver transplantation recipients, and in 141 of the 356 living donor liver transplantation recipients.

Biliary leaks constituted 38% of the post- deceased donor liver transplantation biliary complications
Liver Transplantation

Biliary leaks constituted 38% of the post- deceased donor liver transplantation biliary complications, and 65% of the post-living donor liver transplantation biliary complications.

The median times to first biliary complications were similar for  deceased donor liver transplantation and living donor liver transplantation.

Dr Zimmerman's team commented, "Overall, 1225 diagnostic and therapeutic procedures, including reoperation and retransplantation, were performed."

"The median number of months to the resolution of a biliary complication did not significantly differ between the deceased donor liver transplantation, and living donor liver transplantation groups for leaks or strictures."

"Although the incidence of biliary complications is higher after living donor liver transplantation versus deceased donor liver transplantation, the treatment requirements and the time to resolution after the development of a biliary complication are similar for living donor liver transplantation and deceased donor liver transplantation recipients."

Liver Transplantation 2013:(19):3 :259-267
20 March 2013

Go to top of page Email this page Email this page to a colleague

 25 July 2016 
Antibiotic prophylaxis for open colectomies
 25 July 2016 
Steroids in eosinophilic esophagitis
 25 July 2016 
Prevention of post-ERCP pancreatitis
 22 July 2016 
Upper GI lesions at primary diagnosis in IBD
 22 July 2016 
Fecal calprotectin and IBD
 22 July 2016 
Duodenal villous atrophy and celiac disease
 21 July 2016 
Radiofrequency ablation in Barrett's
 21 July 2016 
HCV eradication and inflammation in cirrhotic patients
 21 July 2016 
Surveillance of Barrett's
 20 July 2016 
Nonselective β-blockers and survival in cirrhosis
 20 July 2016 
Adolescent body mass index and and colorectal cancer risk
 20 July 2016 
Genetic biomarkers and IBD treatment response
 19 July 2016 
Prevention of chemotherapy-induced nausea and vomiting
 19 July 2016 
Longterm clinical follow-up of living liver donors
 19 July 2016 
Screening diabetic patients for NAFLD
 18 July 2016 
Rectal neuroendocrine tumors
 18 July 2016 
Liver stiffness measurement in chronic liver disease
 18 July 2016 
Liver cancer prediction scores in Hep B
 15 July 2016 
Patient reported outcomes in celiac disease
 15 July 2016 
Tonsillectomy and IBD risk
 15 July 2016 
Trainee IBD education in the USA
 14 July 2016 
Screening for familial pancreatic cancer
 14 July 2016 
Fecal calprotection for IBD prognosis
 14 July 2016 
Perianal surgery risk in Crohn's
 13 July 2016 
Lung transplant outcomes in Hep C
 13 July 2016 
Psychological comorbidity and postinfectious IBS
 13 July 2016 
Graft selection strategy in living donor liver transplants
 12 July 2016 
Treatment of pediatric acute liver failure
 12 July 2016 
Therapy for iron deficiency anemia in IBD
 12 July 2016 
Surveillance endoscopy in Barrett's esophagus
 11 July 2016 
Transition to adulthood in celiac disease
 11 July 2016 
Factors that influence access to liver transplant
 11 July 2016 
Disturbed sleep and IBS
 08 July 2016 
Mortality and peptic ulcers
 08 July 2016 
Statins and cirrhosis in Hep B
 08 July 2016 
Genetic risk score and body mass index
 07 July 2016 
Predicting food triggers in eosinophilic esophagitis
 07 July 2016 
Extraperitoneal vs transperitoneal colostomy for hernia
 07 July 2016 
Predictors fecal transplant failure in C. diff infection
 06 July 2016 
Therapies for Hep B cure
 06 July 2016 
Hospital volume and liver cancer survival
 06 July 2016 
Adverse events after outpatient colonoscopy
 05 July 2016 
Colorectal surgery and dialysis
 05 July 2016 
Non-invasive scoring systems for fibrosis in NAFLD
 05 July 2016 
Exercise and gastroesophageal reflux
 04 July 2016 
Guidelines on PPI and NSAID prescription
 04 July 2016 
Rectal cancer surgery checklist
 04 July 2016 
Autoimmunity in eosinophilic esophagitis and families
 01 July 2016 
Outcome measures in celiac disease
 01 July 2016 
Growth factor activity and IBD
 01 July 2016 
Aspirin and colorectal cancer
 30 June 2016 
Staging system for familial adenomatous polyposis
 30 June 2016 
Antibiotics in children and obesity
 30 June 2016 
IBS-type symptoms in pediatric IBD
 29 June 2016 
Hep C eradication in people who inject drugs
 29 June 2016 
Anti-tumor necrosis factor in mothers and newborns
 29 June 2016 
Progression to esophageal carcinoma in Barrett's
 28 June 2016 
Gastric cancer screening in the USA
 28 June 2016 
Cancer recurrence after immune-suppressive therapies
 28 June 2016 
Acute severe ulcerative colitis

Blackwell Publishing


GastroHep.com is a Blackwell Publishing registered trademark
© 2016 Wiley-Blackwell and GastroHep.com and contributors
Privacy Statement
Disclaimer
About Us