Dr Christian Stock from Germany investigated the risk of adverse events requiring hospitalization after screening and nonscreening colonoscopies compared with control subjects who did not undergo colonoscopy.
The research team examined a total of 33,086 individuals who underwent colonoscopy as an outpatient, and 33,086 matched controls who did not undergo colonoscopy.
Outpatient screening and nonscreening colonoscopies.
The team of doctors assessed that the risk of adverse events requiring hospitalization within 30 days after colonoscopy/index date, and risk differences between the group that underwent colonoscopy and the group that did not.
The incidence of perforation was 0.8 and 0.7 per 1000 screening and nonscreening colonoscopies, respectively.
|The incidence of perforation was 0.8 per 1000 screening colonoscopies|
The research team noted that hospitalizations because of bleeding occurred in 0.5 and 1.1 per 1000 screening and nonscreening colonoscopies, respectively.
The incidence of myocardial infarction, stroke, and other non-GI adverse events was similar in colonoscopy and control groups.
No splenic injury was observed.
The doctors examined that those with adverse events generally had a higher mean age and comorbidity rate than the overall study population.
The analysis relies on health insurance claims data.
Dr Stock's team comments, "This study provides further evidence of the safety of colonoscopy in routine practice with regard to delayed and non-GI adverse events."
"Hospitalizations because of the investigated adverse events were uncommon or rare for both screening and nonscreening colonoscopies."