Dr Marte Lie HÝivik from Norway compared the work disability rate in inflammatory bowel disease patients 10 years after disease onset, with the work disability rate in the background population.
The research team assessed whether clinical or demographic factors in the early disease course could predict work disability after 10 years disease.
A large, population-based inception cohort was prospectively followed up at 1, 5 and 10 years after diagnosis.
The researchers collected 10-year follow-up data on work disability.
Data on disability pension in the background population were retrieved from public databases.
The research team assessed that they calculated overall and age-standardized relative risks for disability pension.
Logistic regression analysis was used to examine predictive factors.
|The overall disability rate in the IBD population was 19%|
The doctors reported that a total of 518 patients completed the 10-year follow-up.
The overall disability rate in the inflammatory bowel disease population was 19%, and the relative risk was 1.8 for ulcerative colitis, and 2.0 for Crohn's disease.
The researchers reported that the relative risks for disability pension was highest in patients aged below 40 years while patients aged over 60 years had no increased relative risks.
Steroid treatment at the 1-year follow-up predicted work dissability after 10 years disease in both Crohn's disease and ulcerative colitis.
The doctors found that in ulcerative colitis, increased C-reactive protein or erythrocyte sedimentation rate at diagnosis, early colectomy, and more than 2 relapses during the first year of the disease also predicted work disability .
Dr HÝivik's team concludes, "Ten years after disease onset inflammatory bowel disease patients had an increased relative risks for disability pension as compared with the background population."
"The youngest patients had the highest relative risks. Markers of severe disease course predicted work disability ."