Help
Subscribe


Submit Videos to GastroHep Read For FREE - Our full range of review articles
GastroHep.com - the global online resource for all aspects of gastroenterology, hepatology and endoscopy
GastroHep.com - the global online resource for all aspects of gastroenterology, hepatology and endoscopy Profile of Guido Tytgat Profile of Pete Peterson Profile of Peter Cotton Profile of Roy Pounder

Home

News  
Journals
Review Articles
Slide Atlas
Video Clips
Online Books
Advanced Digestive Endoscopy
Classical Cases
Conference Diary
PubMed
International GH Links
USA GH Links
National GH Links
National GI Societies
Other Useful Links




Emails on Gastroenterology and Hepatology
the National AIDS Treatment Advocacy Project
Visit the gastroenterology section of the EUMS

News

Validation of the GerdQ questionnaire for the diagnosis of GERD

A study published ahead of print in the Alimentary Pharmacology & Therapeutics validates the GerdQ questionnaire for the diagnosis of gastro-esophageal reflux disease.

News image

The diagnosis of gastro-esophageal reflux disease (GERD) remains a challenge as both invasive methods and symptom-based strategies have limitations.

The symptom-based management of gastro-esophageal reflux disease in primary care may be further optimised with the use of a questionnaire.

Dr Jonasson and his colleauges assessed the diagnostic validity of the GerdQ questionnaire in patients with symptoms suggestive of gastro-esophageal reflux disease.

Patients with symptoms suggestive of gastro-esophageal reflux disease without alarm features, underwent upper endoscopy, and if normal, pH-metry.

The research team reported that patients were followed for 4 weeks and gastro-esophageal reflux disease was completed blinded to the investigator at both visits.

Reflux esophagitis or pathological acid exposure was used as diagnostic references for gastro-esophageal reflux disease.

GERD had a high positive predictive value of 92%
Alimentary Pharmacology & Therapeutics

The team of doctors assessed the diagnostic accuracy for gastro-esophageal reflux disease on symptom response to proton pump inhibitor.

Among the 169 patients, a gastro-esophageal reflux disease cutoff 9 gave the best balance with regard to sensitivity, 66%, and specificity, for gastro-esophageal reflux disease.

The research team reported that the high prevalence of reflux esophagitis resulted in a high proportion of true positives, but at the same time a high proportion of false-negatives.

Consequently, gastro-esophageal reflux disease had a high positive predictive value, 92%, but a low negative predictive value, 22%, for gastro-esophageal reflux disease.

The team of doctors found that the symptom resolution on proton pump inhibitor therapy had high sensitivity, 76%, but low specificity, 33%, for gastro-esophageal reflux disease.

Dr Jonasson's team concluded,  "GerdQ is a useful complementary tool for the diagnosis of gastro-esophageal reflux disease in primary care."

"The implementation of GerdQ could reduce the need for upper endoscopy, and improve resource utilization."

"Symptom resolution on proton pump inhibitor did not predict gastro-esophageal reflux disease."

Aliment Pharmacol Ther 2013: 37(1): 564-572
07 February 2013

Go to top of page Email this page Email this page to a colleague

 28 August 2015

Advanced search
 28 August 2015 
Statin use and survival in pancreatic cancer
 28 August 2015 
Bacterial endotoxin and NAFLD
 28 August 2015 
Interferon-free regimens for Hep C
 27 August 2015 
HCV in Egypt
 27 August 2015 
Gene expression for hepatocellular carcinoma
 27 August 2015 
Liver abnormalities in celiac disease
 26 August 2015 
Medical management of diverticular disease
 26 August 2015 
Treatment of erosive esophagitis
 26 August 2015 
Dermatological complications of anti-TNF therapy in IBD
 25 August 2015 
Markers for colorectal cancer screening
 25 August 2015 
Long-term PPI use and serum gastrin levels
 25 August 2015 
Treatment for HCV and HIV-1 co-infection
 24 August 2015 
Treatment for HCV and HIV-1 co-infection
 24 August 2015 
Cirrhosis in Hepatitis C patients
 24 August 2015 
Aspirin use and colorectal cancer survival
 21 August 2015 
Activity indexes in ulcerative colitis
 21 August 2015 
Coffee and gallstone disease
 21 August 2015 
Alcoholic cirrhosis in relapse after liver transplant
 20 August 2015 
Cirrhosis in the USA
 20 August 2015 
Mortality causes in liver cirrhosis
 20 August 2015 
Risk of death in IBD
 19 August 2015 
Predicting intestinal surgery in Crohn's disease
 19 August 2015 
Improved screening colonoscopy quality
 19 August 2015 
Sleep positioning device reduces reflux
 18 August 2015 
Health insurance influences HCV screening outcomes
 18 August 2015 
Somatostatin analogues in polycystic liver disease
 18 August 2015 
Global consensus report on H. pylori gastritis
 17 August 2015 
Biomarker of fibrosis stage in NAFLD
 17 August 2015 
Prognostic score for primary biliary cirrhosis
 17 August 2015 
Measuring subjective health in patients with IBS
 14 August 2015 
Factors that influence ulcerative colitis procedure type
 14 August 2015 
H. pylori in African American and Hispanic veterans
 14 August 2015 
Hep E virus in decompensated chronic liver disease
 13 August 2015 
H. pylori in drinking water
 13 August 2015 
Sofosbuvir-regimens in HCV
 13 August 2015 
IBS among Japanese adolescents
 12 August 2015 
Infliximab in patients in IBD
 12 August 2015 
Peritoneal carcinomatosis in colorectal cancer
 12 August 2015 
Predictors of severity of IBD
 11 August 2015 
H. pylori and immune thrombocytopenic purpura
 11 August 2015 
Chemotherapy and intestinal microbiomes
 11 August 2015 
Sexual dysfunction after rectal cancer treatment
 10 August 2015 
Scoring systems to predict alcoholic hepatitis outcomes
 10 August 2015 
Sofosbuvir-based regimens in veterans with HCV
 10 August 2015 
Predicting lymph node metastasis in T1 colorectal cancer
 07 August 2015 
Factors associated with changes in ulcerative colitis
 07 August 2015 
Bariatric surgery and NASH in obese patients
 07 August 2015 
Caffeine and fibrosis in Hep C
 06 August 2015 
Disparities in colonoscopic examination
 06 August 2015 
Weight loss and NASH
 06 August 2015 
Diagnosis of IBS
 05 August 2015 
Gender differences in fecal immunochemical tests
 05 August 2015 
Adenoma detection rates with a screening colonoscopy program
 05 August 2015 
Extraintestinal manifestations in IBD diagnosis
 04 August 2015 
IBD environmental risk factors
 04 August 2015 
Measuring disease activity in Crohn's
 04 August 2015 
Gastric emptying and hyperglycemia in diabetes
 03 August 2015 
Vaccinations and IBD
 03 August 2015 
Lack of response to therapy in severe ulcerative colitis
 03 August 2015 
Nutritional vs biological therapy in Crohn's

Blackwell Publishing


GastroHep.com is a Blackwell Publishing registered trademark
© 2015 Wiley-Blackwell and GastroHep.com and contributors
Privacy Statement
Disclaimer
About Us