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The impact of ileal pouch-anal anastomosis (IPAA) on long-term outcomes in adults is favorable.
Studies on functional outcome and quality of life in children are sparse.
Dr Osnat Zmora and colleagues evaluated the functional and quality-of-life outcomes after IPAA in children and to investigate the possible correlations between the two.
Standardized validated questionnaires of bowel/psychosocial functioning and quality of life were used to assess outcome.
The researchers conducted this study at a tertiary medical center.
All children who had surgery at the centre at 18 years of age, and were followed up, were included.
The team of doctors used global Assessment of Function Scale questionnaires to evaluate functional outcome.
Quality of life in patients 18 years at the time of follow-up was scored by using the Short Form 36 questionnaire completed by the patients.
The doctors scored the quality of life in the younger patients at the time of follow-up using the Child Health Questionarie-28 filled by the parents.
Data were obtained in 26 patients at a median follow-up of 6 years.
The median age at surgery was 15 years.
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| Quality of life was lower than in 7 of 12 items for those who were younger at the time of follow-up |
| Diseases of the Colon & Rectum |
The doctors found that the quality of life was comparable to the general population for children 18 at the time of follow-up in 7 of 8 items, but was lower than in the general population in 7 of 12 items for those who were younger at the time of follow-up.
The mean functional score was found to be negatively correlated to all 8 Short Form 36 parameters, but only to one of the Child Health Questionarie-28 parameters.
Dr Zmora's team concluded, "The functional outcomes among pediatric patients undergoing IPAA are good."
"Parents’ perception of their child’s quality of life is poorer in comparison with the perception by patients themselves when older and with no correlation to the functional results."
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