Help
Subscribe


Submit Videos to GastroHep Read For FREE - Our full range of review articles
GastroHep.com - the global online resource for all aspects of gastroenterology, hepatology and endoscopy
GastroHep.com - the global online resource for all aspects of gastroenterology, hepatology and endoscopy Profile of Guido Tytgat Profile of Pete Peterson Profile of Peter Cotton Profile of Roy Pounder

Home

News  
Journals
Review Articles
Slide Atlas
Video Clips
Online Books
Advanced Digestive Endoscopy
Classical Cases
Conference Diary
PubMed
International GH Links
USA GH Links
National GH Links
National GI Societies
Other Useful Links




Emails on Gastroenterology and Hepatology
the National AIDS Treatment Advocacy Project
Visit the gastroenterology section of the EUMS

News

GERD in the community and its effects on survival

A study published ahead of print in the Alimentary Pharmacology & Therapeutics investigates the natural history of gastro-esophageal reflux symptoms in the community and its effects on survival.

News image

Gastro-esophageal reflux symptoms are common in the community.

However, few studies have examined their long-term natural history, or impact on survival.

Dr Ford and colleagues examined these issues in individuals recruited into a community-based screening programme for Helicobacter pylori in 1994.

The team obtained data on mortality and cause of death at 10 years from the Office for National Statistics.

Baseline demographic data, lifestyle factors, gastrointestinal symptoms and quality of life were recorded at study entry.

The effect of all these factors on persistent and new-onset Gastro-esophageal reflux symptoms, and 10-year mortality, were examined using univariate and multivariate analysis.

The team of doctors found that of 3967 individuals providing complete gastro-esophageal reflux symptoms data at baseline and 10 years, 549 had gastro-esophageal reflux symptoms at baseline.

0.8% per year developed new-onset gastro-esophageal reflux symptoms
Alimentary Pharmacology & Therapeutics

Of these, 183 had persistent symptoms.

Among 3418 individuals asymptomatic at baseline, approximately 0.8% per year developed new-onset gastro-esophageal reflux symptoms.

The team of doctors identified no predictors of persistent gastro-esophageal reflux symptoms.

The doctors noted that the new-onset symptoms were associated with lower quality of life or presence of irritable bowel syndrome at baseline, and higher body mass index at 10 years.

There were 8331 of 8407 subjects providing complete gastro-esophageal reflux symptoms data at baseline, 1289 of whom were symptomatic.

Presence of gastro-esophageal reflux symptoms at baseline did not affect survival.

Dr Ford's team concluded "Gastro-esophageal reflux symptoms persisted in one-third of individuals, whilst new-onset gastro-esophageal reflux symptoms were associated with poor quality of life, irritable bowel syndrome and higher body mass index."

"Gastro-esophageal reflux symptoms did not impact adversely on survival."

Aliment Pharmacol Ther 2013: DOI: 10.1111/apt.12169
19 December 2012

Go to top of page Email this page Email this page to a colleague

 21 August 2014

Advanced search
 21 August 2014 
Eosinophilic esophagitis
 21 August 2014 
Screening for Barrett’s esophagus
 21 August 2014 
Colorectal cancer mortality in Brazil
 20 August 2014 
Chemotherapy-induced gastrointestinal mucositis
 20 August 2014 
Rectal surgery mortality
 20 August 2014 
Stool methylated DNA markers and colorectal cancer resection
 19 August 2014 
Variability of colonoscopy preparation instructions
 19 August 2014 
Recurrent C. difficile infection in out-patients
 19 August 2014 
Racial disparities and colon cancer
 18 August 2014 
Metabolomic analysis in IBD
 18 August 2014 
Enhanced T-cell response in acute-on-chronic Hep B
 18 August 2014 
The evolution of urban C. difficile
 15 August 2014 
Population-based fecal immunochemical test screening
 15 August 2014 
Abdominal pain in IBS
 15 August 2014 
Gene expression biomarker in ulcerative colitis
 14 August 2014 
Transnasal vs transoral endoscopy
 14 August 2014 
Radiation exposure in gastroenterology
 14 August 2014 
Dietary fibre and diverticular disease
 13 August 2014 
Adherence to Rome criteria in functional dyspepsia
 13 August 2014 
Fecal immunochemical test screening
 13 August 2014 
Flexible sigmoidoscopy screening
 12 August 2014 
Eosinophilic esophagitis and celiac disease
 12 August 2014 
Management of Lynch syndrome
 12 August 2014 
Risk of cancer under immunosuppressive therapy in IBD
 11 August 2014 
Risk of GI bleeds with anticoagulants
 11 August 2014 
Social media in health-care
 11 August 2014 
Gut microbiota in chemotherapy-induced GI mucositis
 08 August 2014 
Surgeon volume and esophagectomy survival
 08 August 2014 
Endoscopy nurse-administered propofol sedation performance
 08 August 2014 
Therapy for biliary tract cancer
 07 August 2014 
Smoking cessation and age of onset of ulcerative colitis
 07 August 2014 
Global consensus on perianal fistulizing Crohn's disease
 07 August 2014 
Colonoscopy length and training duration
 06 August 2014 
Hepatitis C virus infection in the United States
 06 August 2014 
Pediatric to adult IBD care
 06 August 2014 
Biomarker of disease activity in IBD
 05 August 2014 
Rising incidence of celiac disease
 05 August 2014 
Socioeconomic status and IBS
 05 August 2014 
Bowel dysfunction after sphincter-preserving rectal cancer surgery
 04 August 2014 
Relative adrenal insufficiency and chronic liver disease
 04 August 2014 
Colonoscopy screening protocol for liver transplant recipients
 04 August 2014 
Patient-reported outcomes after upper GI bleed
 01 August 2014 
Capsule colonoscopy vs CT colonography for polyp screening
 01 August 2014 
Complications after obesity surgery
 01 August 2014 
Fully covered self-expanding metal stents for benign biliary strictures
 31 July 2014 
Diverticular disease and colon cancer
 31 July 2014 
Biomarkers in liver fibrosis
 31 July 2014 
Risk factors of large colorectal polyps
 30 July 2014 
Interval between screening colonoscopies
 30 July 2014 
Small intestinal permeability in diarrhea predominant IBS
 30 July 2014 
Mineral rich water and constipation
 29 July 2014 
Fluticasone in eosinophilic esophagitis
 29 July 2014 
Causes of GI bleeding in cirrhosis
 29 July 2014 
ALT increases in Hep B
 28 July 2014 
Statins reduce Barrett's
 28 July 2014 
Score predicts risk for Barrett’s esophagus
 28 July 2014 
Gastric cancer prevention
 25 July 2014 
De-escalation of therapy in IBD
 25 July 2014 
Bionic pancreas in type 1 diabetes
 25 July 2014 
Primary care physician counselling and colonoscopy

Blackwell Publishing


GastroHep.com is a Blackwell Publishing registered trademark
© 2014 Wiley-Blackwell and GastroHep.com and contributors
Privacy Statement
Disclaimer
About Us