Help
Subscribe


Submit Videos to GastroHep Read For FREE - Our full range of review articles
GastroHep.com - the global online resource for all aspects of gastroenterology, hepatology and endoscopy
GastroHep.com - the global online resource for all aspects of gastroenterology, hepatology and endoscopy Profile of Guido Tytgat Profile of Pete Peterson Profile of Peter Cotton Profile of Roy Pounder

Home

News  
Journals
Review Articles
Slide Atlas
Video Clips
Online Books
Advanced Digestive Endoscopy
Classical Cases
Conference Diary
PubMed
International GH Links
USA GH Links
National GH Links
National GI Societies
Other Useful Links




Emails on Gastroenterology and Hepatology
the National AIDS Treatment Advocacy Project
Visit the gastroenterology section of the EUMS

News

Prognosis of colorectal cancer in IBD

The latest issue of the Inflammatory Bowel Diseases examines colorectal cancer-associated inflammatory bowel disease.

News image

Few data are available on the incidence, characteristics, treatment, and prognosis of inflammatory bowel disease-associated colorectal cancer (CRC) in population-based cohorts.

Dr Laurent Peyrin-Biroulet from France identified all cases of inflammatory bowel disease-associated colorectal cancer among the 19,451 new cases of colorectal cancer recorded in the Burgundy digestive cancer registry between 1976 and 2008.

The incidence rates were age-standardized according to the world standard population.

Prognosis was determined using univariate and multivariate relative survival.

The research team identified 38 inflammatory bowel disease-associated colorectal cancer.
 
The mean age at colorectal cancer diagnosis was greater for patients without inflammatory bowel disease than those with inflammatory bowel disease.

IBD-associated colorectal cancer per 100,000 was 0.11 for men
Inflammatory Bowel Disease

The doctors found that distributions of gender, stage at presentation, location, and histological type of colorectal cancer did not differ from those of sporadic cases.

The overall world age-standardized incidence of inflammatory bowel disease-associated colorectal cancer per 100,000 was 0.11 for men, and 0.06 for women.

The researchers reported that only age was independently associated with inflammatory bowel disease-associated colorectal cancer.

Treatment modalities did not differ between inflammatory bowel disease and non-inflammatory bowel disease patients.

The team found that a 5-year relative survival was 52% in non-inflammatory bowel disease patients, and 41% in inflammatory bowel disease patients.

After adjustment for age, gender, and stage at diagnosis, the excess hazard of death was about 2 times higher in inflammatory bowel disease than in non-IBD patients.

Dr Peyrin-Biroulet's team concluded that "Apart from age, the characteristics of inflammatory bowel disease-associated colorectal cancer were similar to those of non-inflammatory bowel disease colorectal cancer."

"The prognosis of colorectal cancer may be poorer in patients with inflammatory bowel disease than in those without inflammatory bowel disease."

Inflammatory Bowel Diseases: 18 (12)  2247–2251,
07 December 2012

Go to top of page Email this page Email this page to a colleague

 21 September 2014

Advanced search
 19 September 2014 
Adhesions in abdominal and pelvic surgery
 19 September 2014 
Repeat colonoscopy among US Medicare
 19 September 2014 
Progression to liver cancer in HCV-infected Veterans
 18 September 2014 
Patient improvement following sacral neuromodulation
 18 September 2014 
Autoimmune diseases in functional gastrointestinal disorders
 18 September 2014 
New diagnostic score for hepatic steatosis
 17 September 2014 
Orange juice intake for bowel preparation
 17 September 2014 
Treatment of fistulising perianal Crohn's disease
 17 September 2014 
Interval colorectal cancers
 16 September 2014 
Fiber treats IBS
 16 September 2014 
Resected biliary tract cancer
 16 September 2014 
Postoperative adhesions in digestive surgery
 15 September 2014 
Fecal transplantation for C.diff infection
 15 September 2014 
Prunes and GI function
 15 September 2014 
Antidepressants for IBS
 12 September 2014 
Management of complex colon polyps
 12 September 2014 
Metabolic syndrome delays HBeAg seroclearance
 12 September 2014 
Drug-induced liver disease
 11 September 2014 
Hepatobiliary cirrhosis risk after organ transplant
 11 September 2014 
Sofosbuvir plus peginterferon/ribavirin for HCV
 11 September 2014 
Patient perceptions in celiac disease
 10 September 2014 
Adhesions in abdominal and pelvic surgery
 10 September 2014 
Acute kidney injury after colonoscopy
 10 September 2014 
Management algorithm for endoscopic mucosal resection of colonic lesions
 09 September 2014 
PPIs and spontaneous bacterial peritonitis in cirrhosis
 09 September 2014 
Neutrophil function and mortality in cirrhosis
 09 September 2014 
MELD and liver cancer survival
 08 September 2014 
Vagal nerve blockade and morbid obesity
 08 September 2014 
Comparison of diet programs in overweight and obese adults
 08 September 2014 
Long-term follow-up after bariatric surgery
 05 September 2014 
Healing rates in reflux esophagitis
 05 September 2014 
Progression of environmental enteropathy
 05 September 2014 
Diabetes and liver transplant outcomes
 04 September 2014 
Colectomy rates for refractory ulcerative colitis
 04 September 2014 
Infliximab prevents long-term Crohn’s disease recurrence
 04 September 2014 
Histological recovery with gluten-free diet in celiac disease
 03 September 2014 
Predictors of response in Crohn's disease
 03 September 2014 
Diagnosis of atrophic gastritis
 03 September 2014 
Safety of reinitiation of infliximab therapy
 02 September 2014 
SSRIs and depression in Hep C
 02 September 2014 
Bariatric surgery for obesity
 02 September 2014 
Eosinophilic esophagitis in adults
 01 September 2014 
Risks with anti-TNF in pediatric IBD
 01 September 2014 
Fecal hemoglobin and colorectal cancer screening
 01 September 2014 
Genetic variants in alcoholic liver disease
 29 August 2014 
Gluten-free diet for asymptomatic celiac disease
 29 August 2014 
NSAID-induced small intestinal injury and diaphragm disease
 29 August 2014 
Symptom evaluation in functional dyspepsia
 28 August 2014 
Predictoris of C. diff in out-patients
 28 August 2014 
Detection of gastroesophageal reflux symptoms
 28 August 2014 
Colorectal-cancer mortality after adenoma removal
 27 August 2014 
Endoscopy outcomes in community hospital vs tertiary academic centers
 27 August 2014 
UV exposure and IBD hospitalizations
 27 August 2014 
Hepatocellular carcinoma screening in liver disease
 26 August 2014 
NAFLD and gastroesophageal reflux symptoms
 26 August 2014 
Adalimumab-treated patients with ulcerative colitis
 26 August 2014 
Wound healing after abdominoperineal resection
 25 August 2014 
Surgical management of rectourethral fistulas
 25 August 2014 
Biomarker analysis in biopsies for ulcerative colitis
 25 August 2014 
Ileocolic resection in Crohn's disease

Blackwell Publishing


GastroHep.com is a Blackwell Publishing registered trademark
© 2014 Wiley-Blackwell and GastroHep.com and contributors
Privacy Statement
Disclaimer
About Us