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News

Clinical guideline on the management of Crohn's disease

The Alimentary Pharmacology & Therapeutics reports on the latest NICE clinical guideline on the management of Crohn's disease in adults, children and young people.

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The guideline offers best practice advice on the care of adults, children and young people with Crohn's disease.
 
Professor Mayberry and colleagues from the United Kingdom provided clinically effective and cost-effective evidence-based recommendations to guide clinical practice in a clinical guideline commissioned by the National Institute for Health and Clinical Excellence (NICE).
 
The research team performed a systematic review of the evidence including critical appraisal, meta-analysis and cost-effectiveness modelling.
 
The team identified 31 evidence-based recommendations covering induction and maintenance therapy.

The research team found 5 key priorities for implementation together with 9 future research recommendations.

The team report 3 available guideline versions, including short, full, and an Understanding NICE guidance for patients and carers.

Algorithms have been produced together with a NICE pathway and implementation tools.
 
Professor Mayberry's team concludes, "These are the first evidence-based clinical and cost-effectiveness guidelines for Crohn's disease in the United Kingdom."

Aliment Pharmacol Ther 2012: DOI: 10.1111/apt.12102
27 November 2012

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