Help
Subscribe


GastroHep.com - the global online resource for all aspects of gastroenterology, hepatology and endoscopy

 31 May 2016

Advanced search
GastroHep.com - the global online resource for all aspects of gastroenterology, hepatology and endoscopy Profile of Roy Pounder

Home

News  
Journals
Review Articles
Slide Atlas
Video Clips
Online Books
Advanced Digestive Endoscopy
Classical Cases
Conference Diary
PubMed
International GH Links
USA GH Links
National GH Links
National GI Societies
Other Useful Links




Emails on Gastroenterology and Hepatology
the National AIDS Treatment Advocacy Project
Visit the gastroenterology section of the EUMS

News

Endoscopic submucosal dissection and EMR for early gastric cancer

The most recent issue of the Gastrointestinal Endoscopy performed a meta-analysis of endoscopic submucosal dissection and EMR for early gastric cancer

News image

Endoscopic submucosal dissection was developed to overcome the problem caused by incomplete resection by conventional EMR for early gastric cancer.

The technique of endoscopic submucosal dissection had a relative higher incidence rate of complications such as bleeding and perforation because of its large wound incidence and difficulties.

Dr Jingjing Lian and colleagues from China evaluated the efficacy and safety of endoscopic submucosal dissection and EMR for early gastric cancer.

The team made an overall strategy to search various databases both electronically and manually and assessed the quality of selected articles according to the inclusion and exclusion standard.

The researchers performed a meta-analysis of 9 retrospective studies.

The endoscopic submucosal dissection group had lower recurrence frequency
Gastrointestinal Endoscopy

The patients included 3548 lesions.

Intervention method was endoscopic submucosal dissection or EMR.

The team's main outcome measurements included en bloc resection rate, histologic curative resection rate, complications, and recurrence rate.

The research team identified 9 retrospective studies.

A total of 3548 lesions were enrolled.

The mean time required for resection was longer for endoscopic submucosal dissection  than for EMR.

The en bloc rate in the endoscopic submucosal dissection group was significantly higher than that in the EMR group, and so was the total histologically complete resection rate.

The research team observed that the endoscopic submucosal dissection group had lower recurrence frequency.

The team noted that the perforation rate was higher in the endoscopic submucosal dissection  group, whereas the bleeding incidences were similar between the two groups.

Dr Lian's team concluded, "Compared with EMR for early gastric cancer, endoscopic submucosal dissection showed considerable advantages regarding en bloc resection rate, histologically complete resection rate, and local recurrence even for small lesions, but it had the disadvantages of higher complication rates for perforation."

"All of the results mentioned should be confirmed by well-designed, randomized, controlled trials from more countries, with larger samples and long enough follow-up periods."

Gastrointest Endoscopy 2012: 76(4): 763-70
17 October 2012

Go to top of page Email this page Email this page to a colleague

 31 May 2016 
Markers as a reflection of inflammatory burden in ulcerative colitis
 31 May 2016 
Predicting Crohn's diseases before diagnosis
 31 May 2016 
Biomarker predicts post ERCP pancreatitis
 30 May 2016 
Challenges for direct-acting antivirals in Hep C
 30 May 2016 
Endoscopic indices for disease activity in ulcerative colitis
 30 May 2016 
Colonoscopy reimbursement reduction in practice
 27 May 2016 
Obstructive sleep apnea and NASH
 27 May 2016 
Risk stratification in acute upper GI bleeding
 27 May 2016 
Hepatocellular carcinoma in chronic Hep B patients
 26 May 2016 
Education booklet for colonoscopy bowel preparation
 26 May 2016 
Direct-acting antivirals in Hep C cirrhosis
 26 May 2016 
Uncomplicated diverticulitis in outpatients
 25 May 2016 
PPIs and NSAID-induced small bowel injury
 25 May 2016 
Preventing NSAID-associated GI toxicity
 25 May 2016 
Recurrence of Barrett’s after successful endoscopic therapy
 24 May 2016 
New therapies for NASH
 24 May 2016 
Fecal inflammatory markers in Crohn's
 24 May 2016 
Depression and IBD recurrence
 23 May 2016 
Cancer after colectomy in IBD
 23 May 2016 
Risk factors for peptic ulcer bleeding outcomes
 23 May 2016 
Liver transplantation for hepatocellular carcinoma
 20 May 2016 
Prognostic score for hepatic venous outflow obstruction
 20 May 2016 
Treatment for uncomplicated acute diverticulitis
 20 May 2016 
Biomarker for colorectal cancer diagnosis
 19 May 2016 
Probiotics and H. pylori eradication
 19 May 2016 
Impaired skeletal health in atrophic gastritis
 19 May 2016 
Predicting outcome in ulcerative colitis
 18 May 2016 
Erectile dysfunction in IBD
 18 May 2016 
Acute GERD and esophageal histologic changes
 18 May 2016 
Surgical fundoplication for GERD 
 17 May 2016 
Mucosal dysbiosis in Crohn's disease
 17 May 2016 
Vitamin D level and clinical status in IBD 
 17 May 2016 
Inpatient costs for IBD and acute pancreatitis
 16 May 2016 
Outcomes of postcolonoscopy colorectal cancers
 16 May 2016 
Therapy for Crohn's in a Medicaid population
 16 May 2016 
C. difficile in ulcerative colitis patients
 13 May 2016 
Parkinson's disease and IBD
 13 May 2016 
Inactivated oral cholera vaccine
 13 May 2016 
Non-traditional heart disease risk factors in NAFLD
 12 May 2016 
Gestational diabetes mellitus and NAFLD
 12 May 2016 
Impact of Crohn's in the USA
 12 May 2016 
Ozanimod induction and ulcerative colitis
 11 May 2016 
Anti-TNF discontinuation in IBD
 11 May 2016 
Age and disease presentation with Crohn's disease
 11 May 2016 
Prognosis after colorectal cancer resection
 10 May 2016 
Gluten-free diet in patients with IBS-diarrhea
 10 May 2016 
Noninvasive test for IBD
 10 May 2016 
Digital health for gastroenterology
 09 May 2016 
Diarrheal infections in adults
 09 May 2016 
Quality improvement initiative and readmission for cirrhosis
 09 May 2016 
Coffee or tea and the risk of Barrett's
 06 May 2016 
Risk factors in peptic ulcer bleeding
 06 May 2016 
Recurrent pancreatitis after acute pancreatitis
 06 May 2016 
Managing acute lower GI bleeding
 05 May 2016 
Chemoradiotherapy vs chemotherapy for pancreatic cancer
 05 May 2016 
Genetics in early-early-onset IBD
 05 May 2016 
Reductions in quality of screening colonoscopies
 04 May 2016 
Anti-TNF therapy for IBD
 04 May 2016 
Bismuth and H. pylori eradication
 04 May 2016 
Chromoendoscopy vs colonoscopy for dysplasia in colitis

Blackwell Publishing


GastroHep.com is a Blackwell Publishing registered trademark
© 2016 Wiley-Blackwell and GastroHep.com and contributors
Privacy Statement
Disclaimer
About Us