Colonoscopy preparation usually involves the intake of large volumes of polyethylene glycol electrolyte solution in combination with a clear-liquid diet.
Liberalization of the diet might enhance the tolerance to polyethylene glycol electrolyte solution without compromising the quality of the preparation.
Dr Soweid and colleagues from Lebanon evaluated the efficacy and tolerability of polyethylene glycol electrolyte solution given with a clear-liquid diet compared with a fiber-free diet for colonoscopy preparation.
The incidence of adverse events among patients in the 2 diet groups was also assessed as a secondary outcome.
|Tolerance to the preparation was higher in the fiber-free diet group |
The research team performed a single-center randomized, prospective, single-blind study.
A total of 200 patients undergoing colonoscopy were randomized to either clear-liquid diet or fiber-free diet in addition to polyethylene glycol electrolyte solution.
The researchers noted that patients in the fiber-free diet group were able to drink more polyethylene glycol electrolyte solution compared with those in the clear-liquid diet group.
The research team observed that quality of the preparation was significantly better in the fiber-free diet group, with more patients having satisfactory preparations than those in the clear-liquid diet group.
Tolerance to the preparation was higher in the fiber-free diet group compared with the clear-liquid diet group, with significantly more patients adhering to the fiber-free diet regimen.
The team noted that there were more adverse events experienced in the clear-liquid diet group, with odds ratios of 2 for nausea, 4 for vomiting, and 3 for headache.
Dr Soweid's team concludes, "Fiber-free diet given with polyethylene glycol electrolyte solution on the day before colonoscopy is a more effective regimen than the standard clear-liquid diet regimen, and is better tolerated by patients."