Coffee contains various compounds that have recently been reported to exert beneficial health effects, however, the conclusion of its relation with mortality has not yet been reached.
Dr Kemmyo Sugiyama and colleagues from Japan investigated the associations between coffee consumption, all-cause, and cause-specific mortality in Japan.
The research team included 37,742 participants, of which 18,287 were men and 19,455 were women aged 40–64 years.
The patients had no history of cancer, myocardial infarction, or stroke at baseline, based on the Miyagi cohort study initiated in 1990.
The outcomes were mortality due to all causes, cardiovascular disease, and cancer.
During the 10 year of follow-up, 2454 participants died, including 426 due to cardiovascular disease and 724 due to cancer.
|Death due to cancer was not associated with coffee consumption in men|
|Journal of Nutrition|
In women, the multivariate hazard ratios for all-cause mortality in participants who drank coffee never, occasionally, 1–2 cups, and 3 cups a day were 1, 0.9, 0.8, and 0.75, respectively.
The research team found that the multivariate hazard ratios for cardiovascular disease mortality in women were 1, 0.6, 0.5, and 0.45, respectively for participants who drank coffee never, occasionally, 1–2 cups, and 3 cups a day.
The team noted that of the specific cardiovascular disease, there was a strong inverse association between coffee consumption and mortality due to coronary heart disease in women but not in men.
Death due to cancer was not associated with coffee consumption in either men or women, except for colorectal cancer in women.
Dr Sugiyama's team concluded, “Our results suggest that coffee may have favorable effects on mortality due to all causes and to cardiovascular disease, especially coronary heart disease, in women.”