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 23 April 2018

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News

Abdominal visceral adipose tissue predicts risk of colorectal adenoma

Abdominal visceral adipose tissue predicts risk of colorectal adenoma in both sexes, reports the latest issue of the Clinical Gastroenterology & Hepatology.

News image

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Small studies have shown inconsistent results regarding the association between abdominal visceral adipose tissue and colorectal adenomas.

Dr Su Youn Nam and colleagues from Korea evaluated the effects of visceral adipose tissue volume on the development and growth of colorectal adenomas.

A total of 3922 participants underwent colonoscopy and computed tomography to 2008.

The associations between waist circumference, visceral adipose tissue volume, and colorectal adenomas were estimated.

Waist circumference was associated with colorectal adenomas in men
Clinical Gastroenterology & Hepatology

In addition, the association between characteristics of colorectal adenomas and visceral adipose tissue volume was evaluated.

The research team found that compared with participants who had visceral adipose tissue volume of less than 500 cm3, the odds ratio for colorectal adenoma was 1.09, for a volume of 500 to 999 cm3, 1.33 for a volume of 1000 to 1499 cm3, and 1.43 for a volume of 1500 cm3 or greater.

The risk of colorectal adenomas increased with increasing visceral adipose tissue volume in both sexes.

The research team observed that waist circumference was associated with colorectal adenomas in men, but not in women.

High volume of visceral adipose tissue had a positive association with larger adenomas and multiple adenomas.

Dr Nam's team concluded, “Abdominal visceral adipose tissue volume can contribute to the development and growth of colorectal adenomas.”

“It was a better predictor for risk of colorectal adenomas than body mass index or waist circumference in both sexes.”

Clin Gastroenterol & Hepatol 2010: 8(5): 443-50
03 May 2010

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