|
Dr Carlos Madalosso and colleagues studied the impact of gastric bypass on gastroesophageal reflux disease (GERD) in patients with morbid obesity.
The team assessed the impact of gastric bypass on gastroesophageal reflux disease based on Montreal Consensus.
The team investigated 86 patients for GERD before gastric bypass and 6 months later.
Esophageal and extraesophageal syndromes were assessed based on Montreal Consensus.
Esophageal acid exposure and gastric pouch acidity were also evaluated.
 |
| The overall prevalence of GERD was 64% before gastric bypass |
| Annals of Surgery |
The researchers found that the overall prevalence of GERD was 64% before gastric bypass, and 33% after gastric bypass.
Typical reflux syndrome was present in 55% of patients preoperatively, and disappeared in 79% of patients post-gastric bypass.
The research team found that out of 39 patients with no symptoms, 10% developed typical reflux syndrome postoperatively.
The chief typical reflux syndrome complaint changed from heartburn pre-gastric bypass to regurgitation post-gastric bypass.
Esophageal mucosa improved in 27, was unchanged in 51, and worsened in 8 patients in regard of esophagitis.
The researchers found extraesophageal syndromes were present in 16 patients preoperatively, and in none but 1 post-gastric bypass.
GERD-related well being and use of proton pump inhibitors were both improved after gastric bypass.
The research team observed that the total acid exposure decreased from a median of 5% to 1%.
The researchers observed that 86% showed an acid gastric pouch in fasting conditions post-gastric bypass.
Dr Madalosso's team concluded, “Gastric bypass ameliorated GERD syndromes in most patients 6 months after the procedure, resulting in quality of life improvement and less proton pump inhibitors usage.”
“Whether regurgitation post-gastric bypass corresponds to reflux disease or bad eating behavior deserves further studies.”
| 
Email this page to a colleague
