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Barrett's esophagus is a precursor of esophageal adenocarcinoma, both of which are associated with GERD.
Screening GERD patients for Barrett's esophagus has been suggested, but it is not known which patients should be screened and at what age.
Dr Joel Rubenstein and colleagues determined the age-specific yield of endoscopy for Barrett's esophagus stratified by sex and indication for endoscopy.
The team evaluated a total of 155,641 patients undergoing their first endoscopy at one of the CORI sites for clinical indications.
 | | The yield of Barrett's increases steeply from early to middle adulthood | | Gastrointestinal Endoscopy |
The researchers found that among white men with GERD, the yield of Barrett's esophagus increases steeply from early adulthood to middle adulthood, and then plateaus.
The team observed no difference in the yield of Barrett's esophagus between middle-aged white women with GERD and white men without GERD.
Dr Rubenstein's team concluded, “The yield of upper endoscopy for the diagnosis of Barrett's esophagus increases rapidly among white men with GERD until approximately age 50 and then reaches a plateau.”
“White women with GERD are at no increased risk compared with white men without GERD.”
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