Help
Subscribe


GastroHep.com - the global online resource for all aspects of gastroenterology, hepatology and endoscopy

 25 May 2018

Advanced search
GastroHep.com - the global online resource for all aspects of gastroenterology, hepatology and endoscopy Profile of Roy Pounder

Home

News  
Journals
Review Articles
Slide Atlas
Video Clips
Online Books
Advanced Digestive Endoscopy
Classical Cases
Conference Diary
PubMed
International GH Links
USA GH Links
National GH Links
National GI Societies
Other Useful Links




Emails on Gastroenterology and Hepatology
the National AIDS Treatment Advocacy Project
Visit the gastroenterology section of the EUMS

News

Is PillCam COLON capsule endoscopy ready for colorectal cancer screening?

The latest issue of Endoscopy investigates whether PillCam COLON capsule endoscopy is ready for colorectal cancer screening.

News image

fiogf49gjkf04

Colorectal cancer  screening with colonoscopy was introduced into the National Cancer Prevention Program in Germany in 2002.

Dr Andreas Sieg and colleagues from Germany hypothesized that as compliance for screening is low, colon capsule endoscopy could be an alternative approach.

Feasibility and performance of colon capsule endoscopy  were evaluated in comparison with colonoscopy in ambulatory patients with special attention to a short colon transit time.

The team tested colon capsule endoscopy  in ambulatory patients enrolled for colonoscopy who presented for screening or with positive fecal occult blood test.

Study subjects underwent colon preparation and ingested the capsule in the morning.
The capsule was excreted within 6 hours.
Endoscopy

Colonoscopy was performed after excretion of the capsule.

Colonoscopy and colon capsule endoscopy  were performed by independent physicians who were blinded to the results.

The researchers evaluated in total 38 patients.

Only 1 patient was excluded because the capsule remained in the stomach during the entire period of examination.

Another patient had limited time and the procedure had to be stopped when the capsule was still in the transverse colon.

The team reported the results of 36 patients who successfully completed colon capsule endoscopy, and the conventional colonoscopy examination.

The capsule was excreted within 6 hours in 84% of the patients.

If oral sodium phosphate was excluded from the preparation, the colon transit time increased to a median of 8 hours.

The team identified that 7 of 11 small polyps detected by colonoscopy  by colon capsule endoscopy.

The research team noted that 1 small polyp detected by colon capsule endoscopy was not identified by colonoscopy.

In this series, no large polyps were found, and 1 colorectal cancer  was detected by both methods.

The mean rates of colon cleanliness in the cecum, transverse colon, and in the descending colon were significantly better than in the rectosigmoid colon.

The overall mean rate during colonoscopy was significantly better than during colon capsule endoscopy.

No adverse effects occurred.

Dr Sieg's team concluded, “Colon capsule endoscopy  appears to be a promising new modality for colonic evaluation and may increase compliance with colorectal cancer  screening.”

“To achieve a short colon transit time, sodium phosphate seems to be a necessary adjunct during preparation.”

“The short transit time is a prerequisite to abandon the delay mode of the capsule.”

“With an un-delayed PillCam COLON capsule, a 'pan-enteric' examination of the gastrointestinal tract would be possible.”

“Further studies are needed to improve the cleanliness, especially in the rectum and to evaluate the method as a potential screening tool.”

Endoscopy 2009: 104(4): 848-54
16 April 2009

Go to top of page Email this page Email this page to a colleague

 25 May 2018 
Colorectal cancer–specific mortality
 25 May 2018 
Technology to increase colorectal cancer screening
 24 May 2018 
Patient-reported outcome measures in IBD trials
 24 May 2018 
Alcohol consumption and outcomes in drug-induced liver injury
 24 May 2018 
Precision medicine for tumors
 23 May 2018 
Management of perianal fistulas in Crohn’s disease
 23 May 2018 
Cardiovascular risk in diabetes mellitus with NAFLD
 23 May 2018 
High body mass index is and ulcerative colitis
 22 May 2018 
Worldwide H.pylori prevalence
 22 May 2018 
PPI and risk of stroke
 22 May 2018 
Online tool predicts bowel dysfunction severity prior to anterior resection
 21 May 2018 
Depressive symptoms in IBD youth
 21 May 2018 
PPI use and cognitive decline
 21 May 2018 
Fecal incontinence and quality of life in IBD
 18 May 2018 
Esophageal dilatation in clinical practice 
 17 May 2018 
IBD and later extraintestinal manifestations
 17 May 2018 
Repeat stool DNA testing
 17 May 2018 
IBS and chronic fatigue following GI infection
 16 May 2018 
Factors associated with fecal incontinence
 16 May 2018 
Diagnostic delay in Crohn's disease
 16 May 2018 
Cardiovascular risk in diabetes mellitus with NAFLD
 15 May 2018 
Guidelines for management of Crohn's
 15 May 2018 
Hep B in the Grey Zone
 15 May 2018 
New therapies for CDI
 14 May 2018 
Blood test for the diagnosis of fibrotic NASH
 14 May 2018 
Outcomes at bariatric centers of excellence
 14 May 2018 
Management of perianal fistulas in Crohn’s
 11 May 2018 
Detection of undiagnosed celiac disease
 11 May 2018 
Alcohol consumption and drug-induced liver injury
 10 May 2018 
Post‐operative complications in elderly IBD
 10 May 2018 
Colorectal cancer screening
 10 May 2018 
Fibrosis in patients with chronic hepatitis B
 09 May 2018 
Fecal incontinence
 09 May 2018 
Health problems and IBS
 09 May 2018 
Esophageal dilatation in clinical practice 
 07 May 2018 
Omitting antibiotics in uncomplicated acute diverticulitis
 07 May 2018 
Health problems and IBS
 07 May 2018 
Assessment of diminutive colorectal polyps
 04 May 2018 
National Institutes of Health workshop and obesity
 04 May 2018 
Factors associated with fecal incontinence
 04 May 2018 
Colorectal cancer screening and ethnic inequities
 03 May 2018 
Gastrointestinal ultrasound in IBD
 03 May 2018 
Ultransonography in postsurgical recurrence in Crohn's
 02 May 2018 
Symptom assessment in cirrhotic ascites
 02 May 2018 
Hep C antiviral treatment and liver cancer risk
 02 May 2018 
Chronic Hep B
 01 May 2018 
European guidelines on pancreatic cystic neoplasms
 01 May 2018 
Interferon‐free regimens in Hep C
 01 May 2018 
Age at IBD onset and extraintestinal complications
 30 April 2018 
Formula for preterm infants
 30 April 2018 
Primary antibiotic resistance and sequential therapy for H. pylori
 27 April 2018 
Eastern and western practices for endoscopic resection of colorectal lesions
 27 April 2018 
Anxiety scale for chronic esophageal disease
 27 April 2018 
Disease activity in eosinophilic esophagitis
 26 April 2018 
Obesity and physical activity in diverticulosis
 26 April 2018 
Primary sclerosing cholangitis in the USA
 25 April 2018 
Aspirin and pancreatic cancer
 25 April 2018 
Central mediators of irinotecan-induced steatohepatitis
 25 April 2018 
Neuroimaging in Hep C
 24 April 2018 
Scoring system identifies cancer risk in Barrett's

Blackwell Publishing


GastroHep.com is a Blackwell Publishing registered trademark
© 2018 Wiley-Blackwell and GastroHep.com and contributors
Privacy Statement
Disclaimer
About Us