In tertiary referral patients, there is association between altered sleep patterns, functional bowel disorders and altered gut motor function.
Body mass index is also associated with gastrointestinal symptoms including diarrhoea, and with sleep disturbances.
Dr Cremonini and colleagues from Minnesota, USA hypothesized that sleep disturbances are associated with gastrointestinal symptoms, and this is not explained by body mass index .
A 48-item-validated questionnaire was mailed to 6939 community participants.
The team reported that the survey included gastrointestinal symptoms, sleep disturbance, daily lifestyle and quality of life.
Independent contributions of sleep disturbance to individual symptoms were assessed using logistic regression adjusting for age, gender, lifestyle and mental health status.
The researchers examined the association of an overall sleep score with an overall symptom score.
|27% reported trouble staying asleep|
|Neurogastroenterology & Motility|
In addition, the team also evaluated the ability of both scores to predict Short Form-12 physical and mental functioning scores assessed in multiple linear regression models.
Among 3228 respondents, 27% reported trouble staying asleep.
There was a significant correlation of overall sleep scores with overall gastrointestinal symptom scores.
The team found that waking up once nightly at least 4 times a month was significantly associated with pain, nausea, dysphagia, diarrhoea, loose stools, urgency and a feeling of anal blockage.
Trouble falling asleep was significantly associated with rectal urgency.
The research team noted that associations were independent of gender, age, lifestyle factors and body mass index.
Overall, sleep scores and gastrointestinal symptom scores were both significant independent predictors of impaired quality of life.
Dr Cremonini’s team concluded, “In the community, reporting poor sleep is associated with upper and lower gastrointestinal symptoms, but this is independent of body mass index.”