Management of Helicobacter pylori, a causative agent of gastrointestinal diseases is an important health problem in most countries.
The main reasons include poorly defined epidemiological status and unrecognized mode of bacterial transmission.
Dr Mehdi Nouraie and colleagues from Iran investigated the prevalence of H. pylori infection, and identified possible risk factors for the H. pylori infection.
The team assessed 2561 healthy individuals aged 18 to 65 years out of 12,100,000 inhabitants of Tehran province by cluster sampling.
Infection with H. pylori was evaluated by detection of anti-H. pylori IgG antibody in serum.
|The prevalence of H. pylori infection was 69%|
Sociodemographic status of each subject was determined by filling up a questionnaire.
The researchers found that the prevalence of H. pylori infection was 69%, and that it correlated with increasing age.
The highest infection rate, at 79%, was seen in individuals 46 to 55 years old.
No association was detected between H. pylori positivity and gender.
Low education of the study subjects, low father's and mother's education, poor tooth brushing habit, and crowded families in childhood were determined possible risk factors.
In addition, the team noted that lack of household bath, hygienic drinking water, and sewage disposal facility in childhood were determined as possible risk factors.
Dr Nouraie’s team concluded, “The rate of prevalence of H. pylori infection was higher than developed countries.”
“Low socioeconomic status, poor sanitary indications, and crowded families in childhood were related to high prevalence of H. pylori infection in Iran.”
“Accordingly, fecal–oral and oral–oral routes could be considered as the main pathways of transmission of H. pylori .”