Dr Corley and colleagues from California, USA evaluated the demographics and incidence of Barrett’s esophagus diagnosis using community-based data.
The team assessed incidence and prevalence of a new Barrett’s esophagus diagnosis by race, sex, age and calendar year.
The researchers identified 4205 persons who met the study definition for a diagnosis of Barrett’s esophagus.
|The incidence was 2 per 100,000 for persons aged 21 to 30 years|
The annual incidence in 2006 was highest among non-Hispanic whites, with lower rates among Hispanics, Asians, and blacks.
The team found that the annual incidence was higher among men than women.
The incidence increased with age from 2 per 100, 000 for persons aged 21 to 30 years, to a peak of 31 per 100,000 member-years for persons aged 61 to 70 years.
There was no increase in the incidence of new diagnoses until the last 2 observation years, which coincided with changes in data collection methods and may be due to bias.
The overall prevalence among active members increased almost linearly to 131 per 100,000 member-years by 2006.
Dr Corley’s team concluded, “The demographic distributions of Barrett’s esophagus differ markedly by race, age and sex and were comparable to those for esophageal adenocarcinoma.”
“Thus, demographic disparities in esophageal adenocarcinoma risk may arise partly from the risk of having Barrett’s esophagus, rather than from differing risks of progression from Barrett’s esophagus to cancer.”
“There has been an almost linear increase in the prevalence of diagnosed disease.”