Helicobacter pylori is a prevalent organism implicated in peptic ulcer disease.
Dr Abraham and colleagues from Texas, USA validated administrative data for diagnosis of H. pylori-infected patients.
Administrative data identified patients with ICD-9 code for H. pylori or prescription of eradication therapy.
The team confirmed diagnosis by chart abstraction.
|The positive predictive value of ICD-9 code was 100% if assessed from an in-patient encounter|
|Alimentary Pharmacology & Therapeutics|
Multivariable regression assessed predictors of infection considering drug therapy, ICD-9 code 041.86, and procedure code.
In addition, the researchers evaluated in-patient or out-patient diagnostic code, age, gender and race to generate an algorithm for validation.
The test cohort of 531 patients was primarily male, Caucasian and elderly.
The team noted that the positive predictive value of ICD-9 code 041.86 was 100% and 97% if assessed from an in-patient or out-patient encounter, respectively.
Eradication drug therapy had a positive predictive value of 74% and 98%, measured from an in-patient or out-patient encounter, respectively.
The strongest predictors were out-patient ICD-9 code 041.86, eradication drug therapy, esophagogastroduodenoscopy, and age 70.
An algorithm including these data elements yielded a c-statistic of 0.9, and a positive predictive value of 98%.
Dr Abraham’s team concludes, “Administrative data can diagnose H. pylori-infected patients.”
“The diagnostic algorithm includes presence of eradication drug therapy overlapping with an out-patient ICD-9 code 041.86 among elderly adults.”