Esophageal cancer surgery is often followed by malnutrition, but the factors causing weight loss are unknown.
Dr Martin and colleagues from Sweden undertook a population-based study was to identify such risk factors.
The research team collected data from a nationwide Swedish organization for research on surgery for esophageal cancer.
A total of 340 patients responded to a study-specific questionnaire concerning height and weight, just before and 6 months after surgery.
|Neoadjuvant therapy had a 2-fold increased risk of weight loss|
|British Journal of Surgery|
Factors influencing malnutrition, defined as loss of body mass index of at least 15% at 6 months after operation, were identified by logistic regression.
The researchers associated neoadjuvant therapy and female sex with at least a 2-fold increased risk of weight loss.
In contrast, the team noted that preoperative weight loss was associated with a decreased risk.
Dr Martin's team concluded, “Age, tumor stage and location, type of esophageal substitute, suture technique and postoperative complications did not influence the risk.“
“Neoadjuvant therapy and female sex appear to be associated with an increased risk of malnutrition after esophageal cancer surgery.”