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 19 November 2017

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News

High-definition vs standard endoscopy in the diagnosis of colorectal cancer

This month’s issue of Gastroenterology examines the impact of wide-angle, high-definition endoscopy in the diagnosis of colorectal neoplasia.

News image

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It is essential to optimize standard colonoscopy technique to be able to increase polyp detection.

Dr Maria Pellisé and colleagues from Spain compared the performance of colonoscopy using a high-definition, wide-angle endoscope versus a standard colonoscope for the detection of colorectal neoplasia.

The team included all consecutive consenting adult patients referred from primary care centers.

The patients were randomly assigned at a 1:1 ratio to undergo high-definition, wide-angle endoscope or standard colonoscope .

Times to reach and withdraw from the cecum were measured.

Both techniques detected a similar number and type of lesions
Gastroenterology

Morphology, size, location, and pathologic diagnosis of each polyp were recorded.

Sample size calculation resulted in a total of 682 patients needed.

The researchers found that a total of 693 consecutive patients fulfilled all inclusion criteria.

Each arm included 310 patients with no baseline characteristic differences.

The research team noted that time to reach the cecum was slightly superior for standard colonoscope.

The team reported that pathology examination was feasible in 418 lesions.

Both techniques detected a similar number and type of lesions, and there were no differences in the distribution along the colon, in the degree of dysplasia, or morphology of adenomas.

The per-patient basis analyses demonstrated no differences between the 2 arms of the study in the detection rates of polyps, adenomas, or small adenomas.

The team also noted no differences between the 2 arms of the study in the detection of flat adenomas, or hyperplastic polyps.

Dr Pellisé’s team concluded, “High-definition, wide-angle endoscope did not detect significantly more colorectal neoplasia than standard colonoscope.”

Gastroenterol 2008: 135(4): 1062-8


14 October 2008

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