Various modalities including computer tomography (CT), positron emission tomography, and endoscopic ultrasound are being used for esophageal cancer staging.
Dr Gurpal Singh Sandha and colleagues from Canada compared results of locoregional staging by CT, positron emission tomography, and endoscopic ultrasound with histologic staging.
|Endoscopic ultrasound was successful in 86% of patients|
Patients with esophageal cancer proven by endoscopy and biopsy underwent a computed tomography scan of the chest and abdomen, and a positron emission tomography scan.
Patients with no evidence of distant metastatic disease on CT and positron emission tomography were referred for endoscopic ultrasound for locoregional staging.
The researchers compared the tumor size and lymph node stage as determined by endoscopic ultrasound with surgical pathology or endoscopic ultrasound-guided fine-needle aspiration cytology.
The results of lymph node staging with CT, positron emission tomography, and endoscopic ultrasound were compared with surgical pathology or endoscopic ultrasound-guided fine-needle aspiration cytology.
The team reported that 29 patients underwent endoscopic ultrasound between 2005 and 2006.
The team found that endoscopic ultrasound was successful in 86% of patients.
The research team observed no endoscopic ultrasound-related complications.
The team found that 11 of 16 patients with available lymph node histologic study had confirmed metastasis.
The team identified nodal metastasis by computed tomography in 6 of 11 patients.
Nodal metastasis was noted in 4 of 11 patients by positron emission tomography, and in 10 of 11 patients by endoscopic ultrasound.
Overall accuracy for lymph node staging was 69% for computed tomography, 56% for positron emission tomography, and 81% for endoscopic ultrasound.
The team found that 15 patients had confirmed tumor size staging by surgical pathologic examination.
The percentage of agreement for tumor size staging between endoscopic ultrasound and surgical pathology was 80%.
Dr Sandha's team concluded, "Endoscopic ultrasound is safe and accurate for tumor and node staging in esophageal cancer."
"The combination of computed tomography plus endoscopic ultrasound appears to be accurate for locoregional staging in esophageal cancer."