The incidence of esophageal adenocarcinoma in blacks and Hispanics is well-described.
Racial differences in the risk of Barrett's esophagus have not been directly studied.
Dr Julian Abrams and colleagues from New York, USA determined whether race and ethnicity can be identified as risk factors for the development of metaplasia, neoplastic progression, or both.
|Whites had a higher prevalence of Barrett's esophagus than Hispanic|
|Clinical Gastroenterology & Hepatology|
The research team performed a single center retrospective cross-sectional analysis of all patients who underwent upper endoscopy during a 1-year period.
Patients with a prior endoscopy within 5 years or known Barrett's esophagus, or esophageal adenocarcinoma were excluded.
The team confirmed suspected cases of Barrett's esophagus by pathology report.
A total of 2,100 patients met inclusion criteria.
Whites had a significantly higher prevalence of Barrett's esophagus than Hispanic, and blacks.
The team found that in multivariable analysis, factors associated with decreased risk of Barrett's esophagus were black race, and Hispanic ethnicity.
The researchers assessed that male sex, reflux symptoms, hiatal hernia, and older age were associated with increased risk of Barrett's esophagus.
Dr Abrams' team concluded, "Among patients who undergo upper endoscopy, blacks and Hispanics have a significantly lower prevalence of Barrett's esophagus compared with whites."
"These differences in prevalence are comparable to the relative incidence rates observed with esophageal adenocarcinoma, implying that progression from Barrett's esophagus to adenocarcinoma does not vary by race or ethnicity."
"Reasons for lower rates of Barrett's esophagus in Hispanics and blacks need further investigation."