The incidence of Crohn's disease rose rapidly in industralized countries over the past 50 years.
However, it is unclear whether the incidence is still rising or has reached a plateau.
Dr Dr Barney Hawthorne and colleagues from the United Kingdom identified updated the long-term incidence study of Crohn's disease in Cardiff for 1996 to 2005.
The research team investigated whether the incidence is still rising and studied changes in disease characteristics over time.
|The proportion with colonic disease at presentation continues to rise|
|Alimentary Pharmacology & Therapeutics|
The team reviewed cases by retrospective analysis of hospital records.
The researchers identified 212 cases.
The team found that corrected incidence for this decade was 95%, showing a continuing rise compared to previous decades.
The proportion with colonic disease at presentation continues to rise, with a corresponding fall in those with terminal ileal disease.
The team found that there remains a strong female preponderance as in previous studies.
The team found that the incidence in children under age 16 continues to rise, and the median age at diagnosis has fallen slightly.
Dr Hawthorne's team concluded, "Crohn's disease incidence continues to rise slowly in Cardiff with a continuing increase in those presenting with colonic disease, which is now the commonest disease pattern."