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 25 February 2018

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News

Treatment of HIV-Hep C co-infected patients has changed

The most recent issue of the Journal of Hepatology reports on a survey on the treatment of Hep C in HIV infected patients.

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Dr Patrice Cacoub and colleagues analyzed the barriers to Hepatitis C virus treatment in HIV-Hepatitis C co-infected patients and their evolution between 2004 and 2006.

The team prospectively assessed 380 HIV-Hepatitis C virus co-infected patients in surveys in 2004 and 2006.

44% deemed Hep C treatment questionable in 2006 vs 53% in 2004
Journal of Hepatology

The researchers found that compared to patients in 2004, those in 2006 had negative Hepatitis C virus RNA more often.

The team found the rate of liver biopsy was similar between the two survey periods.

The research team noted that 24% had had a non-invasive liver damage assessment.

The team found the rate of previous treatment for Hepatitis C virus infection was 48% in the 2006 survey vs 26% in the 2004.

The main reasons for Hepatitis C virus non-treatment have changed.

The team noted that 44% deemed the Hepatitis C virus treatment questionable in 2006 vs 53% in 2004.

Lack of liver biopsy was the reason for non-treatment in 18% in 2006 vs 33% in 2004.

Physicians' conviction of poor patient compliance was a reason for non-treatment in 20% in 2006 vs 30% in 2004.

The team found in both surveys, that Hepatitis C virus treated patients were more often of European origin.

Patients in both surveys had better control of HIV infection, and had a liver damage assessment more often.

Dr Cacoub's team concluded, "The care of HIV-Hepatitis C virus co-infected patients has changed significantly in real life."

"These results underline the importance of continuing efforts to educate physicians and patients in order to increase the access of co-infected patients to Hepatitis C virus treatment."

J Hepatol 2007: 48(1): 35-42
18 December 2007

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